摘要
本实验用SOD及其抑制剂DDC分别对Lewis肺癌和A_(549)肺癌细胞进行了实验研究,以观察SOD在肺癌的某些生物学特性中的作用。结果发现,SOD和DDC对Lewis肺癌在C_(57)BL小鼠体内的转移有显著的抑制作用,而且DDC的作用更为明显。同时还发现受SOD和DDC作用后的A_(549)肺癌的增殖受到明显抑制,在裸鼠体内的移植瘤形成率显著降低。
The present study observed the effects of superoxide dismutase (SOD) and itsinhibitor, diethyldithiocarbamate (DDC), on the metastasis of Lewis lung cancer andsome biological characteristics of A_(549) lung cancer cell line. It was found that SODand DDC inhibited significantly the metastasis of Lewis lung cancer in C_(57) mice anddecreased the proliferation of A_(549) lung cancer cell and its transplantation rate in nude
出处
《肿瘤》
CAS
CSCD
北大核心
1992年第5期212-215,共4页
Tumor
基金
国家自然科学基金
