摘要
目的 :探讨垂体后叶素在良性子宫疾病手术操作困难患者中的运用价值。方法 :选取2015年6月-2017年5月我院收治的手术困难良性子宫疾病患者96例为研究对象,按随机数字表法分为观察组和对照组,各48例。对照组在术中使用0.9%氯化钠注射液,观察组使用垂体后叶素稀释液(垂体后叶素6 U+0.9%氯化钠注射液10 m L)。比较两组手术时间、术中出血量、并发症发生情况,并记录观察组用药前后血压、心率(HR)变化情况。结果 :观察组手术时间、术中出血量和术前术后血红蛋白差值均显著低于对照组,差异均有统计学意义(P<0.05)。观察组注射垂体后叶素稀释液后5 min、10 min的收缩压(SBP)、舒张压(DBP)和HR均显著高于用药前,差异均有统计学意义(P<0.05)。用药后25 min的SBP、DBP和HR与用药前无统计学差异(P>0.05)。观察组并发症发生率显著低于对照组(P<0.05)。结论 :对于良性子宫疾病手术操作困难患者,适时注射垂体后叶素稀释液,可以缩短手术时间,减少术中出血量,降低并发症发生率,值得临床运用。
Objective:To investigate the value of pituitrin in operation of benign uterine disease with difficult operation. Methods:96 patients with benign uterine disease with difficult operation from June 2015 to May 2017 were selected and divided into observation group and control group according to the random number table, 48 cases in each group. The control group was used 0.9% sodium chloride injection while the observation group was used pituitrin(6 U pituitrin+10 m L 0.9% sodium chloride injection). The operation time, intraoperative blood loss, complications of two groups were compared, and the blood pressure and heart rate changes in the observation group before and after injecting pituitary were recorded. Results:The operation time, the amount of bleeding during the operation and the difference of hemoglobin before and after the operation of the observation group were significantly lower than those in the control group, and the difference was statistically significant(P<0.05). The SBP, DBP and HR of observation group were significantly higher at 5 and 10 min after injecting pituitary dilution than those before treatment(P<0.05). There was no statistical difference in SBP, DBP and HR between 25 min after medication and before treatment(P>0.05). The incidence of complications in the observation group was significantly lower than that in the control group(P<0.05). Conclusion:Timely injection of pituitrin diluent can shorten the operative time of patients with benign uterine disease with difficult operation, reduce bleeding and reduce the incidence of complications, which is worthy of clinical application.
出处
《中国执业药师》
CAS
2018年第3期10-13,共4页
China Licensed Pharmacist
关键词
良性子宫疾病
手术困难
垂体后叶素
Benign Uterine Diseases
Difficult Operation
Pituitrin
