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肿瘤相关性贫血患者血清促红细胞生成素水平与重组人促红细胞生成素治疗效果的关系 被引量:12

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摘要 目的探讨肿瘤相关性贫血(CRA)患者血清内源性促红细胞生成素(EPO)水平与人重组EPO(rh EPO)治疗效果的关系。方法血红蛋白(Hb)水平<100 g/L的97例CRA患者进行血清EPO检测,与同期Hb正常肿瘤患者血清EPO水平进行对比,对CRA患者予规范化rh EPO治疗。结果 CRA患者平均EPO水平较同期Hb正常肿瘤患者高,内源性EPO水平>504 m IU/ml患者rh EPO治疗效果不佳。CRA患者治疗前铁蛋白、血清铁、总铁结合力和转铁蛋白饱和度水平均低于同期Hb正常肿瘤患者,但不同疗效患者的以上指标的差异无统计学意义(P<0.05)。结论血清EPO水平检测可有效指导CRA患者抗贫血治疗药物选择。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2015年第22期6434-6436,共3页 Chinese Journal of Gerontology
基金 国家自然科学基金(No.81402477) 江苏省自然科学基金青年项目(No.BK20140295)
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