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血清CEA和CA199检测对预测结肠癌复发的评价 被引量:4

Evaluation of Carcinoembryonic Antigen (CEA) and Carbohydrate199 (CA199) Determination in Recurrence After Radical Colonic Cancer Surgery
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摘要 目的 探讨CEA和CA199在预测结肠癌复发中的作用。方法 用RIA法检测 60例结肠癌术后复发患者和 60例非胃肠疾患人群血清中CEA和CA199水平。结果 结肠癌患者血清CEA、CA199水平升高 ,与对照组相比有显著性差异 (P <0 0 1) ,复发时任一指标升高的患者 5 5例 ( 91 7% ) ,CEA升高 5 2例 ( 86 7% ) ,CA199升高 42例 ( 70 % ) ,两者差异具有显著性 (P <0 0 5 )。结论 CEA和CA199对监测结肠癌术后复发具有重要作用 。 Objective To study the clinical values of CEA,CA199 in predicting recurrence of colonic cancer.Methods Radioimmunoassay (RIA) was used to measure serum CEA and CA199 in 60 colonic cancer recurrence patients and 60 non-gastrointestinal patients.Results The serum CEA and CA199 levels in colonic cancer group were significantly higher than those in control group (P<0 01). At least one tumor marker was elevated in 55(91 7%)relapsing patients, and the levels of CEA and CA199 were increased in 52(86 7%) and 42(70%) ones respectively. This difference was statistically significant (P<0 05).Conclusion CEA and CA199 have important significances in predicting recurrence of colonic cancer after curative resection. The CEA was more sensitive than CA199.
出处 《中国医师杂志》 CAS 2003年第7期907-908,共2页 Journal of Chinese Physician
关键词 结肠癌 术后复发 CEA CA199 血清检测 Colonic cancer Recurrence CEA CA199
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  • 1John L. McCall M.B., F.R.A.C.S.,Robert B. Black M.B., F.R.A.C.S.,Caroline A. Rich Dip.App.Sc.,John R. Harvey B.Sc.,Robert A. Baker B.Med.Sc. (Hons.),James M. Watts M.B., F.R.A.C.S.,Professor James Toouli M.B., F.R.A.C.S.. The value of serum carcinoembryonic antigen in predicting recurrent disease following curative resection of colorectal cancer[J] 1994,Diseases of the Colon &amp; Rectum(9):875~881

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