摘要
[目的]分析2015—2018年安徽省癌症早诊早治项目肝癌筛查结果。[方法]对安徽省农村常住居民(35~64岁男性和45~64岁女性)采用问卷调查评估出肝癌高危人群;经知情同意后进行肝脏B超检查及甲胎蛋白(AFP)检测,并对筛查结果进行分析。[结果]共有177 586名目标人群完成流行病学危险因素调查,处于高危风险的有45 893人,高风险率为25.78%。乙肝表面抗原(HbsAg)阳性为11 295人,阳性率为6.36%。对27 794人进行了临床诊断性检查,共检出182例肝癌患者,检出率为0.65%。[结论]宿州市埇桥区等6个地区的肝癌患病风险和检出率较高,有消化系统疾病史人群的HbsAg阳性检出率较高。高危人群进行临床筛查的依从性较低,需要进一步提高居民对癌症早诊早治的认识,完善肝癌筛查机制,从而实现肝癌患者的早发现、早治疗。
[Purpose]To analyze the results of liver cancer screening in rural area of Anhui province from 2015 to 2018.[Methods]The liver cancer screening program was conducted among rural residents(35~64 years of age for male and 45~64 years for female)in Anhui province from 2015 to 2018.The risk of liver cancer was assessed by questionnaire survey in all subjects,and the liver ultrasonography and alpha-fetoprotein(AFP)test were performed for identified high-risk subjects.[Results]The risk assessment was performed in 177 586 participants and 45 893 subjects were identified as high risk of liver cancer(25.78%).The HbsAg positive rate was 6.36%(11295/177586).Among 45 893 high-risk subjects,the clinical diagnostic examination was performed in 27 794 subjects,and 182 case of liver cancer was detected with a detection rate of 0.65%(182/27794).[Conclusion]The results shows that the compliance of clinical examination in high-risk subjects is low,indicating that it is necessary to further improve residents’awareness of early diagnosis and treatment of liver cancer.
作者
查震球
贾尚春
陈叶纪
刘志荣
陈万青
ZHA Zhen-qiu;JIA Shang-chun;CHEN Ye-ji;LIU Zhi-rong;CHEN Wan-qing(Anhui Provincial Center for Disease Control and Prevention,Hefei 230601,China;National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China)
出处
《中国肿瘤》
CAS
CSCD
北大核心
2019年第10期743-748,共6页
China Cancer
基金
协同创新中国医学科学院医学与健康科技创新工程(2019-I2M-2-004)
关键词
肝癌
筛查
乙肝表面抗原
农村地区
安徽
liver cancer
screening
hepatitis B surface antigen
rural areas
Anhui
作者简介
通信作者:刘志荣,E-mail:liuzhirong66@126.com;通信作者:陈万青,E-mail:chenwq@cicams.ac.cn
