摘要
[目的]分析2013—2017年江苏省淮河流域地区早诊早治项目肝癌筛查情况。[方法]通过健康影响因素调查表和乙型肝炎表面抗原(HBsAg)检测,对江苏省淮河流域地区35~64岁常住居民进行患癌风险评估,确定肝癌高危对象;对高危对象进行肝脏B超检查以及甲胎蛋白(AFP)检测。[结果]2013—2017年共有105 380名居民接受风险评估,评估出肝癌高危人群20 534人,高危率为19.5%,其中男性12 594人,女性7 940人。完成临床检查17 715人,筛查率为86.3%,其中男性10 369人,女性7 209人。临床筛查阳性病变158例,阳性病变检出率0.9%。确诊肝癌病例46例,肝癌检出率0.3%,其中男性39例,女性7例。早期肝癌28例,早诊率为60.9%。[结论]江苏省淮河流域地区肝癌高危对象的筛查率比较高,但是检出率和早诊率较低,研究结果为肝癌筛查策略的优化提供重要参考依据。
[Purpose] To analyze the results of liver cancer screening in Huai River areas of Jiangsu Province from 2013 to 2017. [Methods] A questionnaire risk assessment and serological testing for hepatitis B virus surface antigen(HBsAg) were offered for participants aged from 35 to 64 years old in Huai River areas of Jiangsu Province. The identified high-risk subjects received abdominal ultrasonography and alpha-fetoprotein(AFP) examination for clinical diagnosis of liver cancer.[Results] From 2013 to 2017, a total of 105 380 residents were involved in liver cancer risk assessment, and 20 534 subjects(19.5%) were identified as high risk, including 12 594 males and 7 940 females, among which, 17 715 subjects(10 369 males and 7 209 females) completed clinical diagnostic examination, with an overall screening rate of 86.3%. A total of 158 cases of positive lesions were detected, accounting for 0.9%. There were 46 detected cases diagnosed as liver cancer with a detection rate of 0.3%(39 males and 7 females). Among 46 detected cases of liver cancer,there were 28 early cases with an early diagnosis rate of 60.9%. [Conclusion] Although the screening rate of the high-risk population for liver cancer in Huai River areas in Jiangsu Province is high, the detection rate and early diagnosis rate are not satisfactory. The findings will provide references for optimizing effective liver cancer screening strategies over the next few years.
作者
缪伟刚
周金意
韩仁强
俞浩
陶然
万亚男
罗鹏飞
MIAO Wei-gang;ZHOU Jin-yi;HAN Ren-qiang;YU Hao;TAO ran;WAN Ya-nan;LUO Peng-fei(Center for Disease Control and Prevention of Jiangsu Province,Nanjing 210009,China)
出处
《中国肿瘤》
CAS
CSCD
北大核心
2021年第7期511-515,共5页
China Cancer
基金
国家重大公共卫生项目。
关键词
肝癌
早诊早治
筛查
淮河流域
江苏
liver cancer
early diagnosis and treatment
screening
Huai River areas
Jiangsu
作者简介
通信作者:罗鹏飞,E-mail:lpfei215@live.cn。
