摘要
测试比较了γ-氨基丁酸(GABA)受体毒剂阿维菌素、氟虫腈对粘虫的生物活性及体内GABA和谷氨酸(Glu)含量的影响。结果表明,阿维菌素对粘虫5龄幼虫的LD50为0.072μg/头,而氟虫腈则为8.920μg/头;阿维菌素的中毒症状分为麻痹期和死亡期,而氟虫腈的中毒症状可以明显地分为兴奋、痉挛、昏迷和死亡4个阶段。两种药剂均会造成试虫体内GABA和Glu代谢异常,其中阿维菌素可致Glu含量增加约1.8倍,使GABA的含量降低,在深度麻痹期仅为对照的71.3%;而氟虫腈可使Glu的含量先增加,在痉挛期达到对照的1.2倍,后降低至与对照同一水平,GABA则先保持不变,但粘虫昏迷后GABA含量降至对照的76.7%。
The difference in bioactivity , poisoning symptom and effect on content of glutamic acid(Glu) and γ-aminobutyric acid(GABA) in larva of armyworm between abamectin and fipronil were determined and (compared.) The result showed that the LD(50) of abamectin and fipronil to the 5th instar larvae of armyworm were 0.072 and 8.920 μg/larva (respectively.) Abamectin caused insects tested paralysis and death directly, but the poisoning symptom of fipronil could be divided into four stages, exciting, convulsive, faint (prostrate) and dead. They both caused (abnormal) metabolism of Glu and GABA in insects tested. Glu (content) in armyworms treated by abamectin was increased 1.8-fold as much as in check , but GABA content was decreased to 71.3% of check. Fipronil could induce Glu content in insects tested increasing 1.2-fold in convulsion stage as much as in check, but same as check in paralysis stage; in paralysis stage, the GABA content was decreased to 76.7% of check.
出处
《农药学学报》
CAS
CSCD
2003年第4期37-41,共5页
Chinese Journal of Pesticide Science
基金
国家"十五"科技攻关项目(2002BA516A04)资助.
关键词
阿维菌素
氟虫腈
Γ-氨基丁酸
谷氨酸
粘虫
abamectin
fipronil
glutamic acid
γ-aminobutyric acid
Mythimna separata
