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Immunohistochemical Studies of the Expression of Matrix Metalloproteinase-2 and Metalloproteinase-9 in Human Prostate Cancer

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摘要 To study the expression of matrix metalloproteinase-2 and-9in human prostate cancer,matrix metalloproteinase-2 and-9 were immunohistochemically detected in tissues of prostate cancer and benign prostatic hyperplasia(BPH).Our results showed that matrix metalloproteinase-2 and-9levels in prostate cancer were much higher than those in tissues of BPH,with the cancer invasion being positively correlated with the expression of the metalloproteinases.It is concluded that matrix metalloproteinase-2 and-9are better molecular markers,which are of help in the diagnosis and prediction of prognosis of prostate cancer.
作者 ZENG Hanqing XIAO Yajun LU Gongchen CHEN Yong 曾汉青;肖亚军;鲁功成;陈勇
出处 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2003年第4期373-374,379,共3页 华中科技大学学报(医学英德文版)
作者简介 ZENG Hanqing,male,born in 1971,M.D.,Ph.D
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