摘要
观察肾炎湿热证血清sICAM - 1的变化 ,结合肾组织病理探讨ICAM - 1与肾炎湿热证的关系。将肾炎患者 4 8例分为湿热证组 (A组 ,n =30 )与非湿热证组 (B组 ,n =18) ,观察两组血清sICAM - 1的变化和光镜下肾小球内固有细胞增生及炎细胞浸润的程度。结果 :A组血清sICAM - 1高于B组 ,A组固有细胞增生及炎细胞浸润的程度较B组明显 ,P <0 0 5。结论 :肾炎湿热证的存在常常预示着免疫炎症反应和病情的活动 ,sICAM - 1有可能作为肾炎湿热证辨证的一个客观指标。
Objective:To observe the change of serumal solvable intercellular adhesion molecule-1(sICAM-1) in damp-heat syndrome of glomerulonephritis and investigate the relation between ICAM-1 and damp-heat syndrome.Methods:Fourty-eight patients were classified damp-heat syndrome group(A,n=30) and nondamp-heat syndrome group(B,n=18),and to observe the change of sICAM-1 and the morphological chang of kidney in cell proliferation and invasion.Results:The data of sICAM-1 in A group were highter than in B group,and the degree of cell proliferation and invasion in A group were more obvious than in B group,P<0.05.Conclusion:The damp-heat syndrome often remind us of immunity information and active state of glomerulonephritis.SICAM-1 shoud be an objective target to differential diagnose the damp-heat syndrome of glomerulonephritis.
出处
《辽宁中医杂志》
CAS
2003年第11期891-892,共2页
Liaoning Journal of Traditional Chinese Medicine
