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原发性肾小球疾病肾小球内补体成分测定与中医辨证分型的关系 被引量:26

Relationship between TCM syndrome types and contents of complement component in glomerulus of primary glomerulopathy
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摘要 本文测定了81例原发性肾小球疾病患者肾小球内补体成分C_3和C_1q的沉积情况,并探讨了其与中医分型的关系。结果:肾小球内补体C_3沉积阳性者与中医阴虚和气阴两虚密切相关,而与阳(气)虚型关系不密切(P<0.01)。同时肾小球内沉积的C_3和C_1q与中医的湿热密切相关,经统计学处理,湿热组与无明显湿热组均有非常显著的差异,从而提示C_3和C_1q在肾小球内的沉积可以作为湿热的一项客观指标。而且还从病理学角度反映了中医阴虚易兼夹湿热的理论。 Modern western medicine hold the complement,especially for C_3 play a importent role in the cause and development of glomerular disease, The authors exommed the deposition of C_3,C_1q in the glomeruli for 81 cases of glomerular disease,The authors also analysed the correlationship between the deposition of C_3,C_1q in the glomeruli and TCM differatiation classification and each of classifications Companied with invasion of damp- heat.Total of patients were 81 cases,of them,ying deficiency type was 50 cases,both Qi end ying deficiency type was 21 cases,yang deficiency type was 10 cases,Among of three hypes,50 cases companied with invasion of damp-heat.The result showed that the positive deposition of C_3 in glomeruli was 63 cases(77.78%),the positive deposition of C_1q in glomeruli was 21 cases(25.93%).The high positive rate was minly in the crnescent nephritis and MPGN、This result further demonstrated that the complement was closely related with the inflamation of glomeruli.The correlationship study indicuted that the deposition of C_3,C_1q in glomeruli was closely related with invasion of damp-heat of TCM differentiation type,The difference(P<0.05 for C_3,P<0.05 for C_1q) between invasion of damp-heat group and no invasion of damp-heat group was significant.The result meant that the deposition of C_3,C_1q in the glomerali mightbe the object ive proof for invasion of damp-heat.This study also showed that the deposition of C_3 in glomeruli was closely related with ying deficiency type,both Qi and ying deficiency type,but not related with yang deficiency type(P<0.01),This study offered the objective proof that ying dificiency type easily companied with invasion of damp-heat.
作者 刘宏伟
出处 《辽宁中医杂志》 CAS 北大核心 1993年第3期1-4,共4页 Liaoning Journal of Traditional Chinese Medicine
关键词 原发性 肾小球病 补体 中医分型 Primary Glomerulopatny Complement Component Differential Diagnosis and Classification of Traditional Chinese Medicine
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参考文献2

  • 1孙世澜,周朝阳,赵华月.Cl_q肾病的临床与病理[J].临床内科杂志,1989,6(2):24-25. 被引量:1
  • 2毛良,宋菊敏,徐蒿年,陈以平,李志道,沈静芬.的测定及与中医辨证分型的关系[J]辽宁中医杂志,1985(05).

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