摘要
D-柠檬烯是一种天然的单萜烯,广泛存在于柑橘、蔬菜及香料中,具有消炎、抑菌、抗肿瘤等多种功效。其中抗癌是D-柠檬烯的主要药理活性之一,其抗癌机制主要包括化学预防作用、抑制细胞周期与诱导细胞凋亡以及抑制肿瘤转移与侵袭等。由于D-柠檬烯具有来源广泛、安全性好、给药方便等优点,具有良好的开发前景和临床应用价值,亟待深入研究。
D-Limonene, widely present in citrus, vegetables and spices, is a natural monoterpene. It plays an important role in many physiological processes, such as reducing inflammation, minimizing bacterial growth, and inhibiting cancer development. Anticancer effect is the major function of D-limonene by participating in chemical prevention, cell-cycle inhibition, induction of apoptosis, and defense against cancer proliferation and invasiveness. D-Limonene has great prospects for clinical application for its wide distribution, excellent safety, and convenient administration. Therefore, it is worthy of further exploration.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2015年第7期240-244,共5页
Food Science
基金
2012年度国家星火计划项目(2012GA811001)
