摘要
目的 了解人乳头瘤病毒 (HPV)新亚型 (注册号 :AF2 76 910 )的分子流行病学特点。方法 PCR 微孔板杂交检测泌尿生殖道标本、宫颈癌石蜡包埋组织、胃癌组织中HPV新亚型 ,结合临床特征了解其致病特点。结果 2 0 2例经HPV通用引物筛查阳性的泌尿生殖道标本中 ,2例HPV新亚型阳性 ,占 0 .1% ;5 1例宫颈癌石蜡包埋组织中 ,3例HPV新亚型阳性 ,占 5 .9% ;15例胃癌组织 ,未测到HPV新亚型。结论 早在 5年前本地区HPV新亚型就已存在 ;HPV新亚型在宫颈癌组织中被测到 ,可能提示其有致癌作用 ,值得进一步研究。
Objective To learn the molecular epidemiolodic character of the new human papillomavirus subtype. Methods The new human papillomavirus subtype was monitored by polymerase chain reaction for genital tract secretion,paraffin-embeded cervical cancer tissues and gastric cancer tissues,studying the clinical characters of the new human papillomavirus subtype. Results 2 cases new human papillomavirus subtype were positive in 202 cases of human papillomavirus that were screened by common primer,the positive rate was 0.1%;3 cases new human papillomavirus subtype were positive in 51 cases of paraffin-embeded cervical cancer tissues ,the rate of positive was 5.9%;there were no any positive of new human papillomavirus subtype in 15 cases of gastric cancer tissues.Conclusion The new human papillomavirus subtype had persistanted before 5 years in Shaoxing;it perhaps showed that the new human papillomavirus subtype associated with cervical cancer.
出处
《中国实验诊断学》
2003年第4期301-303,共3页
Chinese Journal of Laboratory Diagnosis
