摘要
心血管疾病(cardiovascular diseases,CVDs)作为一类全球多发疾病,其预防与治疗长期受到高度关注。尽管传统治疗方法如药物治疗、外科手术和介入疗法在CVDs治疗领域取得显著进展,但高昂的费用、明显的不良反应及复杂的药物间相互作用等问题仍亟待解决。氧化应激是CVDs发展的关键因素,有效缓解氧化应激反应为寻找新的治疗策略提供了思路。植物精油作为一种天然抗氧化剂,因其独特的生物活性和较低的毒性,在CVDs的预防和治疗中展现出巨大潜力。通过对植物精油相关活性成分在CVDs治疗中的抗氧化机制及其研究进展进行综述,为植物精油作为CVDs辅助治疗提供科学依据,并推动其临床应用。
The prevention and treatment of cardiovascular diseases(CVDs),as a group of globally prevalent diseases,have long received great attention.Although conventional therapies,such as pharmacotherapy,surgery and interventional therapy,have made significant progress in treatment of CVDs,high costs,significant adverse effects and complex drug-drug interactions still need to be addressed.Oxidative stress is a key factor in the development of CVDs,and effective mitigation of oxidative stress provides ideas for finding new therapeutic strategies.As a natural antioxidant,plant essential oils show great potential in prevention and treatment of CVDs due to their unique bioactivity and low toxicity.By reviewing the antioxidant mechanisms of plant essential oil-related active ingredients in treatment of CVDs and their research progress,this review provides a scientific basis for the use of plant essential oils as an adjunctive therapy for CVDs and promote their clinical application.
作者
肖晨韵
邹峥嵘
XIAO Chenyun;ZOU Zhengrong(College of Life Science,Jiangxi Normal University,Nanchang 330022,China)
出处
《中草药》
北大核心
2025年第15期5658-5667,共10页
Chinese Traditional and Herbal Drugs
基金
国家自然科学基金资助项目(31760099)。
关键词
植物精油
心血管疾病
氧化应激
抗氧化
抑制脂质过氧化
essential oils
cardiovascular diseases
oxidative stress
antioxidant
inhibits lipid peroxidation
作者简介
肖晨韵,硕士研究生,研究方向为植物天然产物活性成分。E-mail:1127118824@qq.com;通信作者:邹峥嵘,教授,博士生导师,从事植物天然产物活性成分研究。E-mail:zouzhr@jxnu.edu.cn。
