摘要
目的探讨生化检验在糖尿病诊断中的价值。方法选择65例糖尿病患者设为观察组,再选取体检的健康者65例设为对照组。两组均予以生化检验,比较两组血糖指标[空腹血糖(FBG)、餐后2 h血糖(2 h PBG)],血液生化指标[糖化血红蛋白(HbA1c)、甘油三酯(TG)、总胆固醇(TC)、果糖胺(FMN)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)],口服葡萄糖耐量试验结果,各指标对糖尿病的检出率。结果观察组FBG(9.13±1.14)mmol/L、2 h PBG(11.63±1.58)mmol/L均高于对照组的(4.05±0.57)、(5.42±1.02)mmol/L(P<0.05)。观察组HbA1c(10.34±1.45)%、TG(2.63±0.61)mmol/L、TC(5.57±0.21)mmol/L、FMN(3.26±0.25)mmol/L、LDL-C(3.75±0.58)mmol/L均高于对照组的(5.13±0.24)%、(1.14±0.13)mmol/L、(3.97±0.34)mmol/L、(2.01±0.31)mmol/L、(2.61±0.64)mmol/L,HDL-C(0.94±0.22)mmol/L低于对照组的(1.71±0.39)mmol/L(P<0.05)。观察组口服葡萄糖耐量试验30、60、120、180 min的血糖水平均高于对照组(P<0.05)。观察组中,FMN、TG、HbA1c、口服葡萄糖耐量试验对糖尿病的检出率比较具有差异性(P<0.05)。且FMN、TG、HbA1c对糖尿病的检出率分别为96.92%、98.46%、98.46%,均高于口服葡萄糖耐量试验的84.62%(P<0.05)。结论生化检验能快速、准确诊断出糖尿病,能为后续治疗提供参考,具有较高应用价值。
Objective To explore the value of biochemical test in the diagnosis of diabetes mellitus.Methods 65 diabetic patients were selected as the observation group;65 healthy patients were selected as the control group.Both groups were tested with biochemical tests.Comparison of blood glucose indicators[fasting blood glucose(FBG),2-h postprandial blood glucose(2 h PBG)],blood biochemical indicators[glycated hemoglobin(HbA1c),triglycerides(TG),total cholesterol(TC),fructosamine(FMN),low-density lipoprotein cholesterol(LDL-C),high-density lipoprotein cholesterol(HDL-C)],results of the oral glucose tolerance test between the two groups,as well as the detection rate of each indicator for diabetes.Results The observation group had FBG of(9.13±1.14)mmol/L and 2 h PBG of(11.63±1.58)mmol/L,which were higher than those in the control group[(4.05±0.57)and(5.42±1.02)mmol/L](P<0.05).The observation group had HbA1c of(10.34±1.45)%,TG of(2.63±0.61)mmol/L,TC of(5.57±0.21)mmol/L,FMN of(3.26±0.25)mmol/L,and LDL-C of(3.75±0.58)mmol/L,which were higher than those in the control group[(5.13±0.24)%,(1.14±0.13)mmol/L,(3.97±0.34)mmol/L,(2.01±0.31)mmol/L,and(2.61±0.64)mmol/L];the observation group had a lower HDL-C of(0.94±0.22)mmol/L than(1.71±0.39)mmol/L in the control group(P<0.05).The blood glucose levels at 30,60,120,and 180 min after oral glucose tolerance test in the observation group were significantly higher than those in the control group(P<0.05).In the observation group,there were differences in the detection rates of diabetes by FMN,TG,HbA1c,and oral glucose tolerance test(P<0.05).Furthermore,the detection rates for diabetes by FMN,TG,and HbA1c were 96.92%,98.46%,and 98.46%,which were higher than 84.62%by oral glucose tolerance test(P<0.05).Conclusion Biochemical test can diagnose diabetes mellitus quickly and accurately,which can provide reference for subsequent treatment and has high application value.
作者
项栎
XIANG Shuo(Department of Clinical Laboratory,Nanchang Third Hospital,Nanchang 330009,China)
出处
《中国现代药物应用》
2025年第19期76-79,共4页
Chinese Journal of Modern Drug Application
关键词
糖尿病
生化检验
血糖指标
诊断价值
Diabetes mellitus
Biochemical test
Blood glucose index
Diagnostic value
