摘要
肢端肥大症是一种以生长激素(growth hormone,GH)和胰岛素样生长因子-1(insulin-like growth factor-1,IGF-1)的过量分泌为特征的罕见内分泌疾病,对多个器官系统造成影响,导致死亡风险增加。随着人口老龄化的加剧,老年肢端肥大症患者的数量逐年增加,系统并发症也相对突出,生活质量受到严重影响。但目前关于评估老年肢端肥大症问题的文献数据有限。因此,为更深入了解老年人肢端肥大症,本综述聚焦于老年肢端肥大症的流行病学、诊断、并发症评估和治疗预后等。
Acromegaly is a rare disease characterized by the overproduction of growth hormone(GH)and insulin-like growth factor-1(IGF-1),which affects multiple organ systems and increases mortality risk.As the population ages,the number of elderly patients with acromegaly is rising annually,leading to more pronounced systemic complications and significantly impacting quality of life(QoL).However,there is limited data in the literature regarding the assessment of acromegaly complications in the elderly.Therefore,to enhance our understanding of acromegaly in this demographic,the present review focuses on the epidemiology,diagnosis,complication assessment,and therapeutic prognosis of acromegaly in elderly patients.
作者
刘宇珂
谭惠文
李建薇
Liu Yuke;Tan Huiwen;Li Jianwei(Department of Endocrinology and Metabolism,West China Hospital,Sichuan University,Chengdu 610041,Sichuan,China;Centre of Pituitary Adenoma and Related Diseases,West China Hospital,Sichuan University,Chengdu 610041,Sichuan,China)
出处
《中华老年医学杂志》
北大核心
2025年第8期1144-1148,共5页
Chinese Journal of Geriatrics
基金
四川省科技厅项目(GBKT22014)。
关键词
肢端肥大症
生长激素
并发症
治疗
Acromegaly
Growth hormone
Complications
Treatment
作者简介
通信作者:谭惠文,Email:huiwent2016@scu.edu.cn。
