摘要
目的 观察温通逐瘀方灌肠结合针刺治疗慢性盆腔炎急性发作气滞血瘀证患者的效果及安全性。方法 选择2020年1月至2024年3月收治的气滞血瘀证慢性盆腔炎急性发作患者188例,以信封法平均分为常规组与联合中医组,各94例。常规组予西医常规治疗,联合中医组在常规组基础上给予温通逐瘀方与针刺治疗,比较两组患者临床疗效、治疗前后中医证候(下腹胀痛或刺痛、腰骶胀痛、月经量多或经期延长、胸胁或乳房胀痛、白带量多等)积分变化、白细胞介素-6(IL-6)及肿瘤坏死因子-α(TNF-α)水平变化、腹痛消失时间、白带恢复正常时间、体温恢复正常时间、住院时间;记录两组不良反应发生情况;比较治疗后6个月与1年疾病复发率。结果 联合中医组治疗总有效率[96.81%(91/94)]比常规组[88.30%(83/94)]高(P<0.05)。两组治疗后各项中医证候积分及IL-6和TNF-α均较治疗前下降,且联合中医组低于常规组(P<0.05)。联合中医组临床症状消失或恢复时间及住院时间均较常规组短(P<0.01)。两组不良反应发生率比较差异无统计学意义(P>0.05)。联合中医组随访6个月及1年复发率均低于常规组(P<0.05)。结论 温通逐瘀方灌肠结合针刺治疗慢性盆腔炎急性发作气滞血瘀证效果甚佳,且安全可靠。
Objective To observe the effect and safety of enema with the Wentong Zhuyu formula combined with acupuncture in the treatment of patients with acute attack of chronic pelvic inflammatory disease(CPID)and qi stagnation and blood stasis syndrome.Methods A total of 188 patients with of acute attack of CPID with qi stagnation and blood stasis syndrome admitted from January 2020 to March 2024 were selected and evenly divided into the conventional group and the combined traditional Chinese medicine(TCM)group by the envelope method,with 94 patients in each group.The conventional group was given conventional Western medical treatment,while the combined TCM group was treated with the Wentong Zhuyu formula and acupuncture on the basis of the conventional group.The clinical effect of the patients,the changes in the scores of TCM syndrome(distending or stabbing pain in the lower abdomen,distending pain in the lumbosacral region,heavy menstrual flow or prolonged menstrual period,distending pain in the chest,hypochondrium,or breasts,and increased leukorrhea)before and after treatment,the changes in the levels of interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α),the disappearance time of abdominal pain,the time for vaginal discharge to return to normal,and the time for body temperature to return to normal,and length of hospital stay were compared between the two groups.The adverse reactions of the two groups were recorded,and the disease recurrence rate at 6 months and 1 year after treatment was compared.Results The total effective rate of treatment in the combined TCM group[96.81%(91/94)]was higher than that in the conventional group[88.30%(83/94)](P<0.05).After treatment,the scores of various TCM syndromes,IL-6 and TNF-αin both groups decreased compared with those before treatment,and the scores of the combined TCM group were lower than those of the conventional group(P<0.05).The disappearance or recovery time of clinical symptoms and the length of hospital stay in the combined TCM group were shorter than those in the conventional group(P<0.01).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).The recurrence rates of the combined TCM group at 6-monthand 1-year follow-up were both lower than those of the conventional group(P<0.05).Conclusion Enema with the Wentong Zhuyu formula combined with acupuncture has a very good therapeutic effect on the acute attack of CPID with qi stagnation and blood stasis syndrome,and is safe and reliable.
作者
季静
马蔚蓉
周云
JI Jing;MA Weirong;ZHOU Yun(Department of Gynaecology,the Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Provincial Hospital of Chinese Medicine,Nanjin 210000,China)
出处
《临床误诊误治》
2025年第15期97-101,共5页
Clinical Misdiagnosis & Mistherapy
基金
江苏省卫生健康发展研究中心横向课题(JSHD202330)。
关键词
慢性盆腔炎
急性发作
气滞血瘀证
温通逐瘀方
针刺
白细胞介素-6
肿瘤坏死因子-α
复发
chronic pelvic inflammatory disease
acute attack
qi stagnation and blood stasis syndrome
Wentong Zhuyu formula
acupuncture
interleukin-6
tumor necrosis factor-α
recurrence
作者简介
季静,硕士研究生,主治中医师。主要从事中医妇科方向研究;通信作者:周云,Email:zy13461313230@163.com。
