摘要
目的调查及分析2例非洲输入恶性疟疾,为输入性疟疾的防控和治疗提供建议。方法收集2024年1月武汉市报告的2例个案信息、诊疗过程、流行病学史、实验室检测和临床治疗情况进行整理分析。结果2名病例均为中青年男性,有明确非洲高疟区生活史,且居非洲期间身边有人感染疟疾的情况。病例1:在刚果金卢本巴希工作10个月,回国当天出现不明原因发热,体温最高38.0℃,伴寒战、畏寒、头痛;病例2:在坦桑尼亚工作10个月,途径马来西亚出差6 d,回国前1 d出现乏力症状,回国当天出现不明原因发热,体温最高38.5℃,伴乏力,自行口服退热药,发热症状仍反复。2例病例均在发热第3天入院,镜检发现疟原虫环状体。确诊恶性疟疾后,给予青蒿琥酯及对症治疗,均病情好转并康复出院。结论应持续加强境外输入疟疾疫情风险防范和出国务工人员健康宣教,完善卫生、海关、出入境检验检疫、旅游、商务等部门联防联控机制,并优化配置抗疟药品,提高对输入性疟疾早诊早治的水平。
Objective To investigate and analyze two cases of falciparum malaria imported from Africa,and provide suggestions for the control and treatment of imported malaria.Methods The information,diagnosis and treatment process,epidemiological history,laboratory tests and clinical treatment of 2 cases reported in Wuhan city in January 2024 were collected and sorted out for analysis.Results The two cases were both young and middle-aged men,who had a clear history of living in a high-malaria area in Africa,and the people around them were infected with malaria during their stay in Africa.Case 1,who had worked in Lubumbashi,Democratic Republic of Congo for 10 months,and on the day of returning to China,he developed an unexplained fever of 38.0℃,accompanied by chills and headaches.Case 2,who had worked in Tanzania for 10 months and went on a business trip to Malaysia for 6 days before returning to China.One day before returning to China,experienced fatigue symptoms.On the day of returning to China,he developed an unexplained fever of 38.5℃,accompanied by fatigue,and took antipyretic drugs by himself,but the fever symptoms continued to recur.On the third day of fever,both cases were admitted to the hospital and microscopic examination revealed the presence of Plasmodium ring-shaped body.After the diagnosis of falciparum malaria,the two cases were given artesunate and symptomatic treatment,and their condition improved and they recovered and were discharged from the hospital.Conclusions It was necessary to continuously strengthen the risk prevention of overseas imported malaria and health education for overseas workers,improve the joint prevention and control mechanism among health,customs,entry-exit inspection and quarantine,tourism,commerce and other departments,optimize the allocation of antimalarial drugs,and improve the level of early diagnosis and treatment of imported malaria.
作者
徐帆
杨燕
罗华堂
徐文秀
贾西帅
陈芳
陈瑶
刘聪
XU Fan;YANG Yan;LUO Huatang;XU Wenxiu;JIA Xishuai;CHEN Fang;CHEN Yao;LIU Cong(Qiaokou District Center for Disease Control and Prevention,Wuhan,Hubei 430030,China;Wuhan Center for Disease Control and Prevention,Wuhan,Hubei 430024,China;Hongshan District Center for Disease Control and Prevention,Wuhan,Hubei430070,China)
出处
《热带医学杂志》
2025年第5期710-712,F0004,共4页
Journal of Tropical Medicine
基金
湖北省卫生健康委员会科研项目(WJ2019X001)
武汉现场流行病学培训项目(第四期)。
关键词
非洲
输入性疟疾
恶性疟
武汉市
Africa
Imported malaria
Falciparum malaria
Wuhan city
作者简介
徐帆(1994-),女,硕士,从事传染病预防与控制工作;通信作者:刘聪,E-mail:398507918@qq.com。
