摘要
结直肠癌(colorectal cancer,CRC)是消化道常见的恶性肿瘤之一,其肝转移是导致患者死亡的主要原因。肝转移患者早期缺乏典型临床症状,现有影像学方法检出率有限,生物标志物的研究对于预测治疗反应、监测疾病进展及制定个性化治疗方案至关重要。近年,CRC肝转移标志物的研究取得显著进展,为达到早发现、早诊断、早治疗的目的,本文总结既往研究中与CRC肝转移相关的各类生物标志物,旨在探讨其在CRC肝转移早期诊断中的应用价值,以期为临床实践提供参考。
Colorectal cancer(CRC)is one of the common malignant tumors in the digestive tract,and its liver metastasis is the main cause of death for patients.Due to the lack of typical clinical symptoms in patients with liver metastasis in the early stage,the study of biomarkers is crucial for predicting treatment response,monitoring disease progression,and formulating personalized treatment plans.In recent years,significant progress has been made in the research of CRC liver metastasis biomarkers to achieve the goals of early detection,early diagnosis and early treatment.This article summarizes various biomarkers related to CRC liver metastasis in previous studies,aiming to explore their application value in the early diagnosis of CRC liver metastasis,in order to provide a reference for clinical practice.
作者
弓殷
王学玲
GONG Yin;WANG Xueling(Fenyang College Shanxi Medical University,Fenyang 032200,China;Department of Gastroenterology,Fenyang Hospi-tal,Shanxi Medical University,Fenyang 032200,China)
出处
《内科理论与实践》
2025年第2期178-182,共5页
Journal of Internal Medicine Concepts & Practice
关键词
结直肠癌
肝转移
生物标志物
Colorectal cancer
Hepatic metastases
Biomarker
作者简介
通信作者:王学玲,E⁃mail:wangxueling2315@163.com。
