摘要
目的初步探讨能谱CT单能量成像对不同肝脏肿瘤检出的影响。方法回顾性分析42例肝脏肿瘤患者（14例肝细胞癌、12例肝转移瘤、16例肝血管瘤）的临床和影像资料。患者均行CT能谱成像动脉期、门静脉期和静脉期扫描，获得140kVp混合能量图像和70keV单能量图像。对2组图像进行主观图像质量评分，测量肝实质噪声和肿瘤．肝实质的对比噪声比（CNR），2组间比较采用配对t检验。记录不同肿瘤在不同期相的病灶检出数量，采用百分数进行对比分析。结果在70keV图像和140kVp图像上，不同肿瘤在不同期相的图像质量评分分别为（4．30±0．25）和（3．63±0．22）分；肝实质噪声分别为（8．82±0．82）和（10．66±1．10）；CNR分别为5．39和3．89，70keV图像均优于140kVp图像，差异均有统计学意义（P值均〈0．05）。除动脉期肝转移瘤、动脉期肝血管瘤在2组图像上的检出率相同外，不同肿瘤在不同期相70keV图像的病灶检出率（78％-100％）均高于140kVp图像（65％-96％），以小病灶（〈1cm）检出率增高最为明显（分别为57％-100％和14％～91％）。结论能谱CT 70keV单能量图像通过改善图像质量并增加肿瘤与肝实质的对比，有利于肝脏肿瘤的检出，对检出小病灶更敏感。
Objective To evaluate the effect of spectral CT monochromatic imaging on the detection of hepatic tumors. Methods Forty-two patients with hepatic tumors （14 patients with hepatocellular carcinoma, 12 patients with metastatic tumor, 16 patients with hemangioma） underwent CT spectral imaging. During arterial phase, portal phase and venous phase, 140 kVp polychromatic images and 70 keV monochromatic images were obtained. Paired-sample t tests were used to compare the image quality score, liver noise and tumor-to-liver contrast-to-noise ratio （CNR） between the two image data sets. The detection rates of various tumors during each phase were compared. Results The image quality scores of various tumors during three phases were （4. 30 ± 0. 25） and （3.63 ± 0. 22） averagely for the 70 keV and 140 kVp images. The liver noises were （8.82 ± 0. 82） and （ 10. 66 ± 1.10）, and the CNRs were 5.39 and 3.89, respectively. The image quality score, the liver noise and the CNR of 70 keV images were significantly greater than those of 140 kVp images （P 〈 0. 05）. The detection rates of various tumors during each phase were higher with 70 keV images （78%-100%） than with 140 kVp images （65%-96%）, except the hepatic metastatic tumors and the hepatic hemangiomas during the arterial phase. The detection rate was more increased for the small lesions less than 1 cm （57%-100% vs. 14%-91% ）. Conclusion By substantially improving the image quality and increasing the tumor-to-liver conspicuity, the 70 keV monochromatic imaging of spectral CT improves the detection of hepatic tumors and is more sensitive for the detection of small lesions.
出处
《中华放射学杂志》
CAS
CSCD
北大核心
2011年第8期718-722,共5页
Chinese Journal of Radiology
关键词
肝肿瘤
体层摄影术
X线计算机
对比研究
Liver neoplasms
Tomography, X-ray computed
Comparative study
作者简介
通信作者：周诚，Email：chengzhou2000@yahoo．com
