摘要
目的 探讨保乳手术治疗乳腺癌临床转归影响因素。方法 纳入2017年1月至2022年6月行保乳手术治疗早期乳腺癌患者共150例,分析临床特征资料及随访生存情况;对复发组与未复发组临床特征资料进行比较,采用Cox比例风险模型评估保乳手术临床转归独立影响因素。结果 入选患者术后随访24个月复发复发率为4.67%。单因素分析结果显示,年龄、有无腋窝淋巴结转移、肿瘤最大径及分子分型均与保乳手术治疗乳腺癌临床转归相关(P<0.05)。多因素Cox比例风险模型分析结果显示,年龄、有无腋窝淋巴结转移、肿瘤最大径及分子分型均是保乳手术治疗乳腺癌临床转归独立影响因素(P<0.05)。结论 保乳手术治疗乳腺癌临床转归与年龄、有无腋窝淋巴结转移、肿瘤最大径及分子分型关系密切。
Objective To investigate the influencing factors on clinical outcome of breast cancer treated by breast-conserving surgery.Methods 150 patients with early breast cancer who underwent breast-conserving surgery in our hospital from January 2017 to June 2022 were included.Clinical characteristics and follow-up survival status were analyzed.The clinical characteristics of the recurrent group and the non-recurrent group were compared,and Cox proportional risk model was used to evaluate the independent factors influencing the clinical outcome of breast-conserving surgery.Results The recurrence rate was 4.67%after 24 months of follow-up in all patients.Univariate analysis showed that age,presence or absence of axillary lymph node metastasis,maximum tumor diameter and molecular type were related to the clinical outcome of breast cancer treated by breast conserving surgery(P<0.05).The results of multivariate analysis showed that age,presence or absence of axillary lymph node metastasis,maximum tumor diameter and molecular type were independent factors influencing the clinical outcome of breast cancer treated by breast-conserving surgery(P<0.05).Conclusion The clinical outcome of breast-conserving surgery for breast cancer is closely related to age,presence or absence of axillary lymph node metastasis,maximum tumor diameter and molecular classification.
作者
许孟飞
李静丹
张宝财
饶玲艳
方珍
XU Mengfei;LI Jingdan;ZHANG Baocai(Lishui People's Hospital,Zhejiang 323000,China)
出处
《浙江创伤外科》
2025年第6期1004-1005,1155,共3页
Zhejiang Journal of Traumatic Surgery
基金
浙江省医药卫生科技计划项目(2022KY1439)。
关键词
保乳手术
乳腺癌
复发
影响因素
Breast-conserving surgery
Breast cancer
Recurrence
Influencing factor
