摘要
逍遥散具有神经保护、抗肿瘤、抗抑郁、保肝、调节肠道菌群、抗疲劳等药理作用。基于质量传递与溯源、成分可测性、成分有效性、成分特有性及复方配伍环境五方面对逍遥散的中药质量标志物(Q-marker)进行预测分析,认为芍药苷、白术内酯Ⅰ、白术内酯Ⅱ、白术内酯Ⅲ、甘草苷、甘草酸、柴胡皂苷A、柴胡皂苷D、阿魏酸、Z-藁本内酯、茯苓酸、薄荷脑、6-姜辣素、8-姜酚、10-姜酚可测性较强,可作为逍遥散的Q-marker。
Xiaoyao Powder has pharmacological action such as neuroprotection,anti-tumor,anti-depression,liver protection,regulation of intestinal flora,anti-fatigue and so on.Based on the five aspects of quality transfer and traceability,component measurability,component effectiveness,component specificity and compound compatibility environment,the quality marker(Q-marker)of Xiaoyao Powder was predicted and analyzed.It was considered that paeoniflorin,atractylenolideⅠ,atractylenolidⅡ,atractylenolideⅢ,liquiritin,glycyrrhizic acid,Saikosaponin A,Saikosaponin D,ferulic acid,Z-ligustilide,pachymic acid,Menthol,6-gingerol 8-gingerol and 10-gingerol have strong measurability and can be used as Q-marker of Xiaoyao Powder.
作者
李宁
闫茜
赵曦
常虹
李杏花
Li Ning;Yan Xi;Zhao Xi;Chang Hong;Li Xinghua(Department of Breast Surgery,Changzhi People's Hospital,Changzhi 046000,China;Department of Pharmacy,Changzhi People's Hospital,Changzhi 046000,China;Department of Pharmacy,Baotou Medical College of Inner Mongolia University of Science and Technology,Baotou 014040,China)
出处
《国际中医中药杂志》
2025年第4期566-571,共6页
International Journal of Traditional Chinese Medicine
基金
国家自然科学基金(82060784)
山西省自然科学基金(202303021222376)。
关键词
逍遥散
化学成分
药理作用
质量标志物
综述
Xiao Yao San
Chemical composition
Pharmacological action
Q-marker
Review
作者简介
通信作者:李杏花,Email:Xinghualiabc@163.com。
