摘要
目的评估徐州医科大学附属宿迁医院收治的宫颈癌患者发生术后感染相关危险因素,为避免术后感染提供数据支持。方法收集徐州医科大学附属宿迁医院2018年1月至2023年12月的宫颈癌患者临床资料进行回顾性分析。采集手术切口分泌物,血液培养、尿液培养等样本进行细菌鉴定分析。并对确诊感染的患者进行单因素和多因素logistic回归分析。统计与术后感染的各因素相关性。结果收集的200例患者中发生术后感染18例,感染率为9%。感染部位严重程度依次为手术切口、尿道口、阴道。感染病原菌有革兰氏阳性菌、革兰氏阴性菌及真菌。单因素分析表明,年龄、病情分期、是否化疗、是否贫血、导尿时间、抗生素应用策略及糖尿病史与患者术后感染具有显著相关性(P<0.05)。logistic回归分析表明,年龄、病情分期、是否化疗、是否贫血、导尿时间是发生术后院内感染的独立危险因素。结论宫颈癌根治术容易发生院内感染。引发感染的病原菌种类多,并且诱发感染的危险因素多样.根据本研究的结果可以制定相关预防措施,有助于降低术后感染的发生率。
Objective To collect clinical information on postoperative infections in cervical cancer patients undergoing radical surgery at Xuzhou Medical University Affiliated Suqian Hospital,assess related risk factors,and provide data support for preventing postoperative infections.Methods Clinical data of cervical cancer patients from January 2018 to December 2023 at Xuzhou Medical University Affiliated Suqian Hospital were retrospectively analyzed.Collect surgical incision secretions,blood cultures,urine cultures,and other samples for bacterial identification and analysis,and univariate and multivariate logistic regression analyses were conducted for cases diagnosed with infections.The correlation between various factors and postoperative infections was statistically analyzed.Results Among the 200 patients,18 cases of postoperative infection occurred,with an infection rate of 9%.The severity of the infection site was in the order of surgical incision,urethral opening,and vagina.The pathogens identified included Gram-positive bacteria,Gram-negative bacteria,and fungi.Univariate analysis showed that age,disease stage,chemotherapy status,anemia status,catheterization duration,antibiotic application strategy,and diabetes history were significantly correlated with postoperative infection(P<0.05).Logistic regression analysis indicated that age,disease stage,chemotherapy status,anemia,and catheterization duration were independent risk factors for postoperative nosocomial infection.Conclusion Radical surgery for cervical cancer is prone to nosocomial infections.The pathogens causing infections are diverse,and multiple risk factors contribute to the occurrence of infections.Based on the results,relevant preventive measures can be developed to reduce the incidence of postoperative infections.
作者
朱雯静
付建
王洋
胡军武
方月兰
应小燕
ZHU Wenjing;FU Jian;WANG Yang;HU Junwu;FANG Yuelan;YING Xiaoyan(Obstetrics and Gynecology Department,Suqian Hospital Affiliated to Xuzhou Medical University,Suqian,Jiangsu 223800,China;Obstetrics and Gynecology Department,Second Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu 210003,China)
出处
《转化医学杂志》
2024年第11期1811-1814,共4页
Translational Medicine Journal
基金
2020年度江苏省妇幼健康科研项目和引进新技术(F202031)。
关键词
宫颈癌
宫颈癌根治术
细菌感染
危险因素
Cervical cancer
Cervical cancer radical surgery
Bacterial infection
Risk factors
作者简介
朱雯静,本科,主治医师。主要从事妇产科疾病的诊断诊疗研究;通信作者:应小燕,E-mail:sophie_623@163.com。
