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针灸康复联合通络汤对后循环缺血性孤立性眩晕老年患者预后的影响

The Impact of Acupuncture and Moxibustion Rehabilitation Combined With Tongluo Decoction on the Prognosis of Elderly Patients With Isolated Vertigo Due to Posterior Circulation Ischemia
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摘要 目的探讨针灸康复联合通络汤治疗后循环缺血性孤立性眩晕老年患者的效果。方法选取2022年2月—2023年4月在福建省福清市医院康复科进行治疗的70例后循环缺血性孤立性眩晕老年患者为研究对象。以随机数字表法分为对照组与观察组,各35例。所有患者均接受神经内科治疗,对照组联合应用针灸康复,观察组患者在此基础上联合通络汤治疗。比较2组椎基底动脉血流速度、血管内皮功能指标、血液流变学状态及不良反应。结果治疗后,观察组基底动脉(basilar artery,BA)、右椎动脉(right vertebral artery,RVA)、左椎动脉(left vertebral artery,LVA)值分别为(52.38±3.21)cm/s、(35.38±3.12)cm/s、(34.91±3.35)cm/s,均高于对照组的(49.25±3.27)cm/s、(31.34±3.07)cm/s、(30.44±3.37)cm/s,差异有统计学意义(P<0.05)。观察组一氧化氮(nitric oxide,NO)、血清钙基因相关肽(calcium gene related peptide,CGRP)水平分别为(72.38±5.31)μmol/L、(36.23±5.37)ng/L,高于对照组的(64.35±5.38)μmol/L、(31.35±5.02)ng/L;观察组内皮素-1(endothelin-1,ET-1)水平为(77.89±9.21)ng/L,低于对照组的(90.56±9.24)ng/L,差异有统计学意义(P<0.05)。观察组血细胞比容(hematocrit,HCT)、全血黏度高切、全血黏度低切和血浆黏度分别为(44.35±4.19)%、(3.82±0.36)m Pa·s、(8.10±1.04)m Pa·s、(2.01±0.42)m Pa·s,低于对照组的(47.26±4.27)%、(4.45±0.38)m Pa·s、(9.45±1.06)m Pa·s、(2.46±0.44)m Pa·s,差异有统计学意义(P<0.05)。2组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论针灸康复联合通络汤治疗后循环缺血性孤立性眩晕不但有利于增加脑血流,也有助于改善血管内皮功能。 Objective To explore the effect of acupuncture and moxibustion rehabilitation combined with Tongluo decoction on elderly patients with isolated vertigo due to posterior circulation ischemia.Methods A total of 70 elderly patients with isolated vertigo due to posterior circulation ischemia who were treated in the department of rehabilitation,Fuqing City Hospital,Fujian Province from February 2022 to April 2023 were selected as the study objects.They were divided into control group and observation group by random number table method,35 cases in each group.All patients received neurological treatment,the control group combined with acupuncture and moxibustion rehabilitation,the observation group combined with Tongluo decoction treatment on this basis.The blood flow velocity of vertebrobasilar artery,vascular endothelial function index,hemorheology status and adverse reactions were compared between the two groups.Results After treatment,basilar artery(BA),right vertebral artery(RVA)and left vertebral artery(LVA)in the observation group were(52.38±3.21)cm/s,(35.38±3.12)cm/s and(34.91±3.35)cm/s,respectively,which were higher than(49.25±3.27)cm/s,(31.34±3.07)cm/s and(30.44±3.37)cm/s in the control group,and the differences were statistically significant(P<0.05).The levels of nitric oxide(NO)and calcium gene related peptide(CGRP)in the observation group were(72.38±5.31)μmol/L and(36.23±5.37)ng/L,respectively,which were higher than(64.35±5.38)μmol/L and(31.35±5.02)ng/L in the control group,and the endothelin-1(ET-1)level in the observation group was(77.89±9.21)ng/L,which was lower than(90.56±9.24)ng/L in the control group,and the differences were statistically significant(P<0.05).Hematocrit(HCT),high whole blood viscosity,low whole blood viscosity and plasma viscosity in the observation group were(44.35±4.19)%,(3.82±0.36)mPa·s,(8.10±1.04)mPa·s,(2.01±0.42)mPa·s,respectively,which were lower than(47.26±4.27)%,(4.45±0.38)mPa·s,(9.45±1.06)mPa·s,(2.46±0.44)mPa·s in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Acupuncture and moxibustion rehabilitation combined with Tongluo decoction can not only increase cerebral blood flow,but also improve vascular endothelial function after treatment of isolated vertigo due to posterior circulation ischemia.
作者 林春 张媛媛 LIN Chun;ZHANG Yuanyuan(Department of Rehabilitation,Fuqing City Hospital,Fujian Province,Fuqing Fujian 350300,China)
出处 《中国卫生标准管理》 2024年第23期151-154,159,共5页 China Health Standard Management
关键词 孤立性眩晕 后循环缺血 通络汤 针灸 血管内皮功能 脑血流 isolated vertigo posterior circulation ischemia Tongluo decoction acupuncture and moxibustion endothelial function of blood vessels cerebral blood flow
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