摘要
命门-肾气-天癸学说是以命门为核心的中医学理论,体现了中医的整体观念和阴阳调和的思想。特发性性早熟的病机关键为肾的阴阳失调,症状则表现为全身的阴阳失调。现代西医研究证实中枢性性早熟的发病机制为下丘脑-垂体-性腺轴功能失调所致。笔者认为命门-肾气-天癸体系作为以肾藏象为核心的理论,涵盖了下丘脑-垂体-性腺轴的功能,命门-肾气-天癸的功能失调在特发性性早熟的各个阶段均有体现。该文尝试从特发性性早熟的发病机制、命门-肾气-天癸与下丘脑-垂体-性腺轴的关系出发,探讨特发性性早熟的不同时期的病证特点以及对于临床治疗的启发。
The theory of Mingmen-kidney Qi-Tiangui is a traditional Chinese medicine theory with Mingmen as the core,reflecting the overall concept of traditional Chinese medicine and the idea of harmony between Yin and Yang.The key to the pathogenesis of idiopathic precocious puberty is Yin and Yang imbalance of kidney,and the symptoms are Yin and Yang disorders of the whole body.Modern Western medicine studies have confirmed that the pathogenesis of central precocious puberty is caused by hypothalamus-pituitary-gonad axis dysfunction.The author believes that the theory of Mingmen-kidney Qi-Tiangui sys⁃tem covers the function of the hypothalamus-pituitary-gonad axis.As a theoretical system,it is the core of theory of organ pic⁃ture of kidney.The disorders of Mingmen-kidney Qi-Tiangui is reflected in all stages of idiopathic precocious puberty.This article tried to explore the characteristics of different periods of idiopathic precocious puberty and the inspiration for clinical treat⁃ment which was based on the relationship between the pathogenesis of idiopathic precocious puberty,Mingmen-kidney Qi-Tian⁃gui and hypothalamus-pituitary-gonad axis.
作者
沈志坚
徐丽
SHEN Zhijian;XU Li(Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China;Second Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110034,Liaoning,China)
出处
《实用中医内科杂志》
2024年第12期72-75,共4页
Journal of Practical Traditional Chinese Internal Medicine
基金
国家自然科学基金青年科学基金项目(81603511)。
关键词
命门-肾气-天癸学说
特发性性早熟
病证特点
临床治疗
Mingmen-kidney Qi-Tiangui theory
idiopathic precocious puberty
characteristics of disease and syndrome
clinical treatment
作者简介
沈志坚(1998-),男,江苏泰州人,硕士在读,研究方向:中医中药防治小儿常见内科疾病;通讯作者:徐丽(1980-),女,辽宁沈阳人,主任医师、教授,博士研究生导师,博士,研究方向:中医中药和外治法防治儿童常见病、多发病和疑难病,儿童中医藏象理论。E-mail:xu⁃li18940158762@163.com。
