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加味黄芪建中汤联合温针灸对脾胃虚寒证慢性胃炎患者的影响

Effect of Supplemented Huangqi Jianzhong Decoction Combined with Warm Acupuncture and Moxibustion on Patients with Chronic Gastritis of Spleen and Stomach Deficiency Cold Syndrome
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摘要 目的探讨加味黄芪建中汤联合温针灸对脾胃虚寒证慢性胃炎患者的影响。方法选取该院2020年3月—2023年5月收治的68例脾胃虚寒证慢性胃炎患者为研究对象,按随机数字表法将其分为对照组与观察组,各34例。对照组采用常规西医治疗,观察组在对照组基础上加以加味黄芪建中汤联合温针灸治疗,两组均持续治疗2周。对比两组患者胃镜下炎性反应改善情况、中医证候评分、胃黏膜功能、不良反应发生情况。结果治疗后,观察组胃镜下炎性反应改善总有效率为94.12%,高于对照组的76.47%,差异有统计学意义(P<0.05)。治疗后,观察组胃痛隐隐、食欲不振、恶心呕吐、泛吐清水、腹泻评分分别为(1.36±0.15)分、(1.27±0.14)分、(1.38±0.19)分、(1.07±0.11)分、(1.17±0.13)分,均低于对照组的(2.28±0.26)分、(2.05±0.29)分、(2.16±0.24)分、(1.83±0.15)分、(1.99±0.24)分,组间差异有统计学意义(P<0.05)。治疗后,观察组胃蛋白酶原Ⅱ为(14.29±1.87)ng/mL,低于对照组的(18.41±2.56)ng/mL,胃蛋白酶原Ⅰ、胃泌素-17分别为(126.97±10.59)ng/mL、(389.89±28.86)ng/L,均高于对照组的(100.58±8.25)ng/mL、(348.63±25.41)ng/L,组间差异有统计学意义(P<0.05)。两组不良反应发生率对比,差异无统计学意义(P>0.05)。结论加味黄芪建中汤联合温针灸可减轻脾胃虚寒证慢性胃炎患者胃部炎症,缓解症状,改善其胃黏膜功能,且无严重不良反应。 Objective To investigate the effects of supplemented huangqi jianzhong decoction combined with warm acupuncture on patients with chronic gastritis of spleen and stomach deficiency cold syndrome Methods A total of 68 patients with chronic gastritis with spleen and stomach deficiency cold syndrome admitted to the hospital from March 2020 to May 2023 were selected as the research objects,and were divided into a control group and an observation group according to random number table method,with 34 cases in each group.The control group was treated with conventional western medicine,and the observation group was treated with supplemented huangqi jianzhong decoction combined with warm acupuncture and moxibustion on the basis of the control group.Both groups were treated for 2 weeks.The improvement of gastroscopic inflammatory response,TCM syndrome score,gastric mucosal function and occurrence of adverse reactions were compared between the two groups.Results After treatment,the total effective rate was 94.12%in the observation group,which was higher than 76.47%in the control group,the difference was statistically significant(P<0.05).After treatment,the scores of stomachache,dull appetite,nausea and vomiting,water vomiting and diarrhea in the observation group were(1.36±0.15)points,(1.27±0.14)points,(1.38±0.19)points,(1.07±0.11)points and(1.17±0.13)points,respectively,which were lower than(2.28±0.26)points,(2.05±0.29)points,(2.16±0.24)points,(1.83±0.15)points,(1.99±0.24)points in the control group,the differences between the two groups were statistically significant(P<0.05).After treatment,the pepsinogen-Ⅱin the observation group was(14.29±1.87)ng/mL,which was lower than(18.41±2.56)ng/mL in the control group,the levels of pepsinogen-Ⅰand gastrin-17 were(126.97±10.59)ng/mL and(389.89±28.86)ng/L,respectively which were higher than(100.58±8.25)ng/mL and(348.63±25.41)ng/L in the control group,with statistical significances(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Supplemented huangqi jianzhong decoction combined with warm acupuncture and moxibustion can relieve gastric inflammation,relieve symptoms and improve gastric mucosa function in patients with chronic gastritis of spleen and stomach deficiency cold syndrome,without serious adverse reactions.
作者 刘文斌 孙维娟 LIU Wenbin;SUN Weijuan(Department of Internal Medicine of Traditional Chinese Medicine,Dongfang Hospital Jiaozhou Hospital Affiliated to Tongji University,Qingdao 266300,China)
出处 《反射疗法与康复医学》 2024年第16期1-4,共4页 Reflexology And Rehabilitation Medicine
关键词 慢性胃炎 脾胃虚寒证 加味黄芪建中汤 温针灸 Chronic gastritis Spleen and stomach deficiency cold syndrome Supplemcnted huangqi jianzhong decoction Warm moxibustion
作者简介 刘文斌(1972-),男,山东青岛人,本科,主治医师,研究方向:中医内科疾病诊疗。
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