摘要
目的探讨中药熏蒸联合睑板腺按摩对中老年患者睑板腺功能障碍(MGD)干眼症的疗效。方法选取2021年11月1日至2023年10月31日在该院眼科就诊的90例MGD患者为研究对象,根据随机数字表法分为常规组、对照组和观察组,每组30例。常规组使用0.3%玻璃酸钠滴眼液并给予单纯睑板腺按摩,对照组在常规组基础上给予单纯水蒸气熏蒸联合睑板腺按摩,观察组在对照组基础上给予中医熏洗联合睑板腺按摩。比较治疗前及治疗后1、4周3组国际眼表面疾病指数(OSDI)积分、睑缘形态、泪液分泌试验(SIt)、泪膜破裂时间(BUT)、荧光素眼表活体染色(FL)变化情况。结果OSDI积分、睑缘形态评分、SIt、BUT、FL评分在不同组别和治疗时间中存在交互作用(P<0.01),且主效应显著。与治疗前比较,治疗后1、4周3组OSDI积分、睑缘形态评分和FL评分降低,且观察组最低,而SIt水平和BUT升高,且观察组最高,差异有统计学意义(P<0.05)。与常规组比较,对照组、观察组有效率更高(83.33%vs.96.67%vs.76.67%),且观察组高于对照组,差异有统计学意义(P<0.05)。结论中药熏蒸联合睑板腺按摩较单纯睑板腺按摩对MGD干眼症患者眼部症状及泪液分泌水平改善更明显。
Objective To investigate the curative effect of traditional Chinese medicine fumigation combined with meibomain gland massage in the middle-aged and elderly patients with meibomain gland dysfunction(MGD)dry eye syndrome.Methods Ninety patients with MGD visiting in the ophthalmology department of this hospital from November 1,2021 to October 31,2023 were selected as the study subjects and divided into the routine group,control group and observation group according to the random number table method,30 cases in each group.The routine group used 0.3%Sodium Hyaluronate Eye Drops and simple meibomain gland massage.The control group was given the simple vapor fumigation combined with meibomain gland massage on the basis of the routine group.The observation group was given the Chinese medicine fumigation and washing combined with meibomain gland massage on the basis of the control group.The changes of OSDI score,tear secretion test(SIt),breakup time of tear film(BUT)and fluorescein eye surface staining before treatment and in 1,4 weeks after treatment were compared among the three groups.Results The OSDI score,eyelid margin morphology score and scores of SIt,BUT and FL had the interaction in different groups and treatment time(P<0.01),moreover the main effect was remarkable.Compared with before treatment,the OSDI score,eyelid margin morphology score and FL score in 1,4 weeks after treatment in the three groups were decreased,moreover the observation group was the lowest,while the SIt level and BUT were increased,moreover the observation group was the highest,and the differences were statistically significant(P<0.05).Compared with the routine group,the effective rate in the control group and observation group was higher(83.33%vs.96.67%vs.76.67%),moreover the observation group was higher than the control group,and the differences were statistically significant(P<0.05).Conclusion The traditional Chinese medicine fumigation combined with meibomian gland massage could significantly improve the ocular symptoms and improvement of tear secretion level in the patients with MGD dry eye.
作者
史亮亮
金瑛
赖婷媛
SHI Liangliang;JIN Ying;LAI Tingyuan(Department of Ophthalmology,Second Affiliated Hospital of Zhejiang University of Chinese Medicine,Hangzhou,Zhejiang 310005,China;Department of Nursing,Second Affiliated Hospital of Zhejiang University of Chinese Medicine,Hangzhou,Zhejiang 310005,China)
出处
《重庆医学》
CAS
2024年第21期3274-3278,共5页
Chongqing Medical Journal
基金
浙江省中医药科技计划项目(2020ZB110)。
关键词
中药熏蒸
睑板腺按摩
睑板腺功能障碍
干眼症
疗效
traditional Chinese medicine fumigation
meibomian gland massage
meibomian gland dysfunction
dry eye syndrome
efficacy
作者简介
通信作者:赖婷媛,E-mail:shuiping_422@163.com。
