摘要
目的:探讨N-末端脑钠肽前体(NT-proBNP)、甘油三酯/高密度脂蛋白胆固醇(TG/HDL-C)在老年2型糖尿病(T2DM)合并高血压左室重构预测中的应用价值。方法:选取2021年2月—2024年2月北京市朝阳区安贞社区卫生服务中心收治的79例老年T2DM合并高血压患者作为观察组,另选取同期收治的79例T2DM患者作为对照组。所有受试者进行心脏超声检查,并检测NT-proBNP、TG、HDL-C水平及心室重构指标[左心房内径(LAD)、左室舒张末内径(LEEVD)及左室射血分数(LVEF)],计算TG/HDL-C。采用Pearson相关系数法分析NT-proBNP、TG/HDL-C与心室重构指标的相关性。结果:观察组NT-proBNP、TG/HDL-C、LAD、LVEDD水平高于对照组,LVEF水平低于对照组(P<0.001)。Pearson分析结果显示,NT-proBNP、TG/HDL-C与LAD、LVEDD呈正相关,与LVEF呈负相关(P<0.001)。结论:NT-proBNP、TG/HDL-C在老年T2DM合并高血压左室重构预测中的应用价值较高,可作为心室重构的辅助预测指标。
Objective:To investigate the application value of N-terminal brain natriuretic peptide precursor(NT-proBNP)and triglyceride/high-density lipoprotein cholesterol(TG/HDL-C)in predicting left ventricular remodeling in elderly patients with type 2 diabetes mellitus(T2DM)complicated with hypertension.Methods:A total of seventy-nine elderly T2DM patients with hypertension admitted to Beijing Chaoyang District Anzhen Community Health Service Center from February 2021 to February 2024 were selected as the observation group,and another seventy-nine T2DM patients admitted during the same period were selected as the control group.Cardiac ultrasound was performed in all subjects,and the levels of NT-proBNP,TG,HDL-C and ventricular remodeling indexes[left atrial inner diameter(LAD),left ventricular end-diastolic inner diameter(LEEVD)and left ventricular ejection fraction(LVEF)]were detected.The TG/HDL-C was calculated.Pearson correlation coefficient method was used to analyze the correlation between NT-proBNP,TG/HDL-C and ventricular remodeling indexes.Results:The levels of NT-proBNP,TG/HDL-C,LAD and LVEDD in the observation group were higher than those in the control group,and the levels of LVEF were lower than those in the control group(P<0.001);the results of Pearson analysis showed that NT-proBNP and TG/HDL-C were positively correlated with LAD and LVEDD,but negatively correlated with LVEF(P<0.001).Conclusion:NT-proBNP and TG/HDL-C have high application value in predicting left ventricular remodeling in elderly patients with T2DM complicated with hypertension,and can be used as auxiliary predictors of ventricular remodeling.
作者
郑宇
刘思雨
Zheng Yu;Liu Siyu(Department of Clinical Laboratory,Beijing Chaoyang District Anzhen Community Health Service Center,Beijing 100011,China)
出处
《中国社区医师》
2024年第27期109-111,共3页
Chinese Community Doctors
关键词
2型糖尿病
高血压
N-末端脑钠肽前体
甘油三酯
高密度脂蛋白胆固醇
左室重构
Type 2 diabetes
Hypertension
N-terminal brain natriuretic peptide precursor
Triglycerides
High density lipoprotein cholesterol
Left ventricular remodeling
作者简介
通信作者:刘思雨。
