摘要
随着人类社会的不断进步发展,为了适应生产生活的需要,机动车也随之变得越来越普及,机动车尾气在2014年被列为2B级致癌物,其中柴油车尾气颗粒物在2012年从2A类致癌物升为1类致癌物。机动车尾气中的颗粒物还会吸附不同种类的致癌物,进一步加强对人体的危害。流行病学研究表明,机动车尾气对循环系统、呼吸系统、神经系统及生殖系统产生损伤效应并诱导疾病的发生,此外机动车尾气还与炎症反应的发生以及一些细胞蛋白的表达翻译异常有密切关系。目前对于机动车尾气有关健康效应的研究尚处于发展阶段,机动车尾气及其他污染物联合毒性效应及机制的研究还需要进一步探讨。该文综述了近年来机动车尾气颗粒物的健康效应及机制研究进展。
With the continuous progress and development of human society,in order to meet the needs of human production and life,motor vehicles have become more and more popular,motor vehicle exhaust was listed as 2B class carcinogen in 2014,of which diesel vehicle exhaust particulate matter was upgraded from 2A carcinogens to 1 class carcinogens in 2012.The particulate matter in motor vehicle exhaust will also adsorb different types of carcinogens,further enhancing the harm to the human body.Epidemiological studies have shown that motor vehicle exhaust has a damaging effect on the respiratory system,circulatory system,nervous system and reproductive system and inducing the occurrence of diseases.In addition,motor vehicle exhaust is also closely related to the occurrence of inflammatory response,as well as the abnormal expression and translation of some cellular proteins.At present,the research on the health effects of motor vehicle exhaust is still in the development stage,and the research on the combined toxic effects and mechanisms of motor vehicle exhaust and other pollutants needs to be further explored.In this paper,the related studies that have been conducted in recent years were reviewed in detail.
作者
陈中豪
王新怡
刘梦可
吕正梅
王牧笛
CHEN Zhong-hao;WANG Xin-yi;LIU Meng-ke;LV Zheng-mei;WANG Mu-di(Department of Histology and Embryology,School of Basic Medical Sciences,Anhui Medical University,Hefei,Anhui 230032,China;不详)
出处
《环境与健康杂志》
CAS
2024年第6期544-550,共7页
Journal of Environment and Health
基金
安徽高校自然科学研究项目(KJ2021A0209)
安徽医科大学博士科研资助基金(XJ201923)。
关键词
大气颗粒物
机动车尾气颗粒
健康效应
Atmospheric particulate matter
Motor vehicle exhaust particles
Health effects
作者简介
陈中豪(2002-),男,本科生,从事环境毒理学研究。通信作者:王牧笛,E-mail:wangmudi@ahmu.edu.cn。
