摘要
结核病(TB)是由结核分枝杆菌(MTB)感染引起的严重威胁人类健康的慢性传染病。自然杀伤(NK)细胞作为先天免疫的重要组成部分,在应对MTB感染时,NK细胞可分化出不同亚群,表现出受体和功能的多样性;并通过分泌细胞因子,串联其他免疫细胞发挥对MTB的抗感染作用,从而增强机体的抗MTB免疫应答反应。
Tuberculosis(TB)is a chronic infectious disease caused by Mycobacterium tuberculosis(MTB)infection and poses a serious threat to human health.Natural killer(NK)cells,an important component of innate immunity,can differentiate into various subpopulations in response to MTB infection,showing a diversity of receptors and functions.They engage in crosstalk with other immune cells by secreting cytokines,thereby exerting anti-infective actions against MTB infection and enhancing the body’s immune response to the infection.
作者
任芹
杨国平
REN Qin;YANG Guoping(Department of Medical Microbiology and Immunology,School of Basic Medicine,Dali University,Dali 671000,China)
出处
《细胞与分子免疫学杂志》
CAS
CSCD
北大核心
2024年第7期660-665,共6页
Chinese Journal of Cellular and Molecular Immunology
基金
云南省地方本科高校联合专项面上项目(2017FH001-085)
大理大学高层次人才资助项目(KYBS201708)
大理大学临床分子免疫学创新团队(ZKLX2019105)。
作者简介
任芹(1999-),女,云南临沧人,硕士研究生,Tel:18887208708,E-mail:18887208708@163.com;通讯作者:杨国平,E-mail:qjygpp33@163.com。
