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难治性类风湿关节炎临床治疗研究概况

Progress in Clinical Treatment of Refractory Rheumatoid Arthritis
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摘要 难治性类风湿关节炎是经传统抗风湿药物治疗后无改善或无法耐受药物的类风湿关节炎,目前无特效药。临床治疗以抗生素、病情缓解抗风湿药、激素、生物制剂等西药为主,危急重症采用免疫吸附、关节微创、血浆置换、干细胞移植等有创治疗快速缓解症状,再在辨证论治基础上采用中药、针灸等辅助西医治疗。然临床仍存在价格高、不良反应多、患者依从性差等问题,该文从西药、有创、中医治疗等方面做难治性类风湿关节炎临床治疗综述如下,以兹为临床优化治疗提供一定思路。 Refractory rheumatoid arthritis is rheumatoid arthritis that does not improve after treatment with tradi-tional antirheumatic drugs or cannot tolerate the drugs.There is currently no specific drug.Clinical treatment is mainly based on Western medicines such as antibiotics,disease-modifying anti-rheumatic drugs,hormones,and biological agents.In critical and severe cases,invasive treatments such as immunoadsorption,minimally invasive joints,plasma exchange,and stem cell transplantation are used to quickly relieve symptoms,and then traditional Chinese medicine is used based on syndrome differentiation and treatment.Acupuncture and other auxiliary Western medicine treatments.However,there are still problems in clinical practice such as high price,many adverse reactions,and poor patient com-pliance.This article summarizes the clinical treatment of refractory rheumatoid arthritis from the aspects of Western medicine,invasive medicine,and traditional Chinese medicine treatment,in order to provide some guidance for clinical optimization of treatment.ideas.
作者 王珍珍 徐卫东 WANG Zhenzhen;XU Weidong(Jiangxi University of Traditional Chinese Medicine,Jiangxi Nanchang 330004,China;Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine,Jiangxi Hospital of Traditional Chinese Medicine,Jiangxi Nanchang 330006,China)
出处 《中医药临床杂志》 2024年第6期1182-1187,共6页 Clinical Journal of Traditional Chinese Medicine
基金 国家自然科学基金委员会地区基金项目(82260909) 国家自然科学基金委员会地区基金项目(81860823) 江西中医药大学校级研究生创新专项(JZYC21S27)。
关键词 难治性 类风湿关节炎 临床治疗 中医治疗 Refractory Rheumatoid arthritis Clinical treatment Traditional Chinese medicine treatment
作者简介 王珍珍,女。研究方向:中医内科,风湿免疫方向。E-mail:2543657424@qq.com。
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