摘要
反流性食管炎(RE)是胃食管反流病的一种重要亚型,发病率呈逐年升高的趋势。近年来,中医药对RE的治疗取得了良好的成效,然而RE的发病机制复杂,涉及到的通路繁多,文章主要总结以下NLRP3/Caspase-1,NF-κB、HIF-2α、P38MAPK信号通路以及经方治疗对以上通路的干预作用,为中医药治愈RE提供科学依据。
Reflux esophagitis(RE)is an important subtype of gastroesophageal reflux disease,and its incidence is increasing year by year.In recent years,traditional Chinese medicine has achieved good results in the treatment of reflux esophagitis,many scholars have discussed how traditional Chinese medicine intervenes in the mechanism of RE pathway,however,the pathogenesis of RE is complex,involving a wide range of pathways.The study mainly summarizes the following NLRP3/Caspase-1,NF-κB,HIF-2αand P38MAPK signaling pathway and the intervention effect of meridian treatment on the pathway above,providing scien⁃tific basis for the cure of RE by traditional Chinese medicine.
作者
王敏
王爱民
徐心怡
杨欣
吴婷婷
朱惠萍
胡绍江
孙宏文
Wang Min;Wang Aimin;Xu Xinyi(Suzhou Hospital of Traditional Chinese Medicine Affiliated to Nan-jing University of Chinese Medicine,Suzhou,Jiangsu,215007,China)
出处
《黑龙江医学》
2024年第11期1401-1403,共3页
Heilongjiang Medical Journal
关键词
反流性食管炎
中医药
信号通路
Reflux esophagitis
Traditional Chinese medicine
Signaling pathway
作者简介
通信作者:孙宏文,E-mail:shw8101@163.com。
