摘要
柴胡桂枝干姜汤临床疗效确切,自汉代至今广为流传记载,是一首被历代医家推崇的柴胡类方,已被收录于2023年8月国家中医药管理局公布的《古代经典名方目录(第二批)——汉族医药》。笔者采用文献计量学的方法,搜集并纳入明确记载方名及药物组成的柴胡桂枝干姜汤相关古籍文献数据共有37处,涉及中医古籍34部。该文从柴胡桂枝干姜汤的方源方名、组成、药物基原、剂量、制法用法、古今主治功效及临床应用分析等方面进行梳理考证。考证结果显示柴胡桂枝干姜汤出自汉代张仲景所著《伤寒论》,药物基原古今基本一致,古籍中药物剂量大多数与《伤寒论》所载用量一致,柴胡桂枝干姜汤功效为和解少阳,温化水饮。主治病证范围广泛,但总以太阳少阳枢机不利为主。该方现代应用范围涉及消化系统、呼吸系统、皮肤科、神经系统等,对于疑难杂症亦有良效。通过对柴胡桂枝干姜汤古籍文献的挖掘梳理,确定其关键信息,以期为经典名方的临床应用及新药研发提供科学参考。
Chaihu Guizhi Ganjiangtang with a definite clinical effect has been widely used and recorded since the Han Dynasty.As a classic prescription of Chaihu classic formula praised by doctors ofsuccessive generations,it has been included in the Ancient Classic Prescription Catalogue(Second Batch):Han Medicine published by the National Administration of Traditional Chinese Medicine in August 2023.We carried out a bibliometric study involved 34 ancient books of traditional Chinese medicine,with 37 records including the name and composition of the prescription.This paper summarizes the source name,composition,original medicinal plant,dose,preparation method,usage,ancient and modern indications,and clinical application of Chaihu Guizhi Ganjiangtang.The results of textual research show that Chaihu Guizhi Ganjiangtang is derived from the Treatise on Febrile Diseases(Shanghanlun)written by ZHANG Zhongjing in the Han dynasty,and the original plants of medicines in this prescription are basically the same in ancient and modern times.Most records about the doses in ancient books are consistent with those in the Treatise on Febrile Diseases(Shanghanlun).The efficacy of Chaihu Guizhi Ganjiangtang is to harmonize lesser yang and resolve water retention by warming.This prescription was used to treat a variety of diseases,especially those caused by disturbance of Qi movement in the greater Yang and lesser Yang.It is now mainly used to treat the diseases in the digestive system,respiratory system,dermatology,nervous system,etc.,being effective for difficult and complicated diseases.Through the excavation and combing of the ancient records of Chaihu Guizhi Ganjiangtang,this paper clarifies the key information,providing a reference for the clinical application of classical prescriptions and the development of new drugs.
作者
王雪洁
梁绿圆
曹佳蕾
刘澜
李维笑
王艺萍
魏炳琦
马丙祥
史文丽
WANG Xuejie;LIANG Lyuyuan;CAO Jialei;LIU Lan;LI Weixiao;WANG Yiping;WEI Bingqi;MA Bingxiang;SHI Wenli(School of Pediatrics,Henan University of Chinese Medicine,Zhengzhou 450046,China;Traditional Chinese Medicine School,Henan University of Chinese Medicine,Zhengzhou 450000,China;The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450000,China)
出处
《中国实验方剂学杂志》
CAS
CSCD
北大核心
2024年第12期136-146,共11页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家自然科学基金项目(81973904)
河南省特色骨干学科中医学学科建设项目(STG-ZYX06-202144)。
关键词
柴胡桂枝干姜汤
经典名方
文献考证
古今应用
Chaihu Guizhi Ganjiangtang
classical prescription
textual research
ancient and modern application
作者简介
第一作者:王雪洁,在读硕士,从事中医药防治儿童神经系统疾病研究,E-mail:xuejie5280@126.com;通信作者:马丙祥,主任医师,教授,从事中医药防治儿童神经系统疾病研究,Tel:0371-66211081,E-mail:mbx1963@126.com;通信作者:史文丽,主治医师,讲师,从事中医药防治儿童神经精神系统疾病,E-mail:shiwenliwendy@163.com。
