摘要
目的 对杨志敏教授门诊治疗中青年失眠的方剂进行数据挖掘,探究杨志敏教授治疗中青年失眠的用药规律。方法 通过收集杨志敏教授近2021年1月1日—2023年1月1日门诊医案,筛选中药方剂治疗中青年失眠的医案。采用Excel整理统计所有方药的信息,包括中药的使用频率、归经、功效,利用IBM SPSS Statistics 27进行聚类分析,运用IBM SPSS Modeler 18.0进行关联规则分析及关联网络图绘制,分析杨志敏教授治疗中青年失眠的使用的中药间的联系和规律。结果 共纳入272个医案,中药的总频次为2452次。高频中药分别是炙甘草、桂枝、生姜、人参、黄芩、大枣、半夏、赤芍等;归经首归脾经,补虚类药物利用度最高,其次是解表药、清热药,药性药味最常用温甘,关联程度最高的主要药对为炙甘草-人参、生姜-大枣、大枣-半夏-黄芩等。结论 杨志敏教授治疗中青年失眠药物多以调和营卫、益气补血、平调寒热等为主,主要药物包括桂枝、炙甘草、人参、生姜、大枣、半夏、柴胡等。
Objective This study aimed to utilize data mining techniques to analyze Professor Yang Zhi-min′s outpatient treatment for insomnia in the middle-aged and young population.Specifically,the study seeks to explore the medication patterns employed by Professor Yang in treating this age group.Methods Outpatient medical records of Professor Yang Zhi-min were collected from January 1,2021 to January 1,2023,and cases where traditional Chinese medicine(TCM)prescriptions were used to treat insomnia in young and middle-aged adults were screened.The information of all prescriptions,including usage frequency,TCM properties,and therapeutic effects,was organized and analyzed using Excel.Cluster analysis was performed using IBM SPSS Statistics27,while association rule analysis and network graph drawing were conducted using IBM SPSS Modeler18.0.The connections and patterns among the TCM herbs used by Professor Yang Zhi-min in treating insomnia in young and middle-aged adults were analyzed.Result A total of 272 medical records were included,with a cumulative count of 2452 instances of Chinese herbal medicine use.The high-frequency TCM herbs were prepared licorice,cinnamon twig,ginger,ginseng,scutellaria baicalensis,jujube,pinellia ternata,and radices paeoniae rubra.Among the meridians,the spleen meridian exhibited the highest utilization of tonifying deficiency drugs,followed by exterior-releasing drugs and heat clearing drugs.The most commonly used medicinal properties and flavors were warm and sweet.The main drug pairs with the highest degree of correlation were roasted licorice-ginseng,ginger-jujube,and jujube-pinellia-baicalensis.Conclusion Professor Yang Zhi-min treatment for insomnia in middle-aged and young adults mainly focuses on harmonizing nutrient and defense Qi,nourishing Qi and blood,and regulating cold and heat.The key herbs employed include cinnamon twig,prepared licorice,ginseng,ginger,jujube,pinellia ternata,and bupleurum hinense.
作者
朱焕颖
原嘉民
朱娟娟
杨志敏
ZHU Huan-ying;YUAN Jia-min;ZHU Juan-juan;YANG Zhi-min(The Second Clinical School of Guangzhou University of Traditional Chinese Medicine,Guangzhou Guangdong 510405;Guangdong Provincial Hospital of Traditional Chinese Medicine,Guangzhou Guangdong 510120;Acupuncture and Moxibustion Rehabilitation Clinical Medical College of Guangzhou University of Traditional Chinese Medicine,Guangzhou Guangdong 510405)
出处
《世界中西医结合杂志》
2024年第5期879-883,894,共6页
World Journal of Integrated Traditional and Western Medicine
基金
广东省中医院临床研究专项(YN10101913、YN2022QN29)
2020年度中医药古籍文献和特色技术传承专项(GZY-KJS-2020-071)。
关键词
中青年
失眠
中药
关联规则
聚类分析
Middle-aged and Young Adults
Insomnia
Traditional Chinese Medicine
Association Rules
Cluster Analysis
作者简介
通信作者:杨志敏,Email:yangyovip@126.com。
