摘要
利尿剂是住院心力衰竭(heart failure,HF)特别是急性失代偿心力衰竭(acute decompensated heart failure,ADHF)患者容量管理的基石。利尿剂抵抗(diuretic resistance,DR)表现为对利尿剂的反应减低甚至完全失效,不仅导致住院时间延长,还使病死率和再住院率增加。目前国内外尚缺乏对HF患者DR诊断和管理的共识。本共识梳理DR的定义、机制、诊断和管理等方面内容,并基于临床研究结果和专家经验,提出相应的处理建议,旨在提高临床医师对DR的认识,并规范DR治疗。
Diuretics play a crucial role in volume management for hospitalized patients with heart failure(HF),particularly those with acute decompensated HF(ADHF).Diuretic resistance(DR),manifested as a diminished response or even a failure to diuretics,which not only prolongs in-hospital stay but also increases mortality and rehospitalization.There is not yet a consensus regarding the diagnosis and management of DR in heart failure patients.Therefore,this consensus focuses on elucidating the definition,mechanisms,diagnosis,and management of DR.Based on clinical research findings and expert experiences,it offers recommendations for treatment,aiming to enhance physicians'awareness and standardize the management.
出处
《临床心血管病杂志》
CAS
2024年第4期257-267,共11页
Journal of Clinical Cardiology
基金
北京市自然科学基金-海淀原始创新联合基金(No:L222006)。
关键词
心力衰竭
利尿剂抵抗
容量管理
heart failure
diuretic resistance
volume management
作者简介
通信作者:杨杰孚,E-mailyangjiefu2011@126.com;通信作者:廖玉华,E-mail:liaoyuh@163.com;通信作者:董蔚,E-mail:301dongw@sina.com。
