摘要
人类病毒性呼吸道疾病是一类广泛流行的传染性疾病,呼吸道病毒感染的发病率在全球居民发病率总体结构中占据主要地位,是导致人类急性和致死性疾病的主要病因之一。天然产物结构多样、作用机制新颖,具有调节机体免疫与抗呼吸道病毒的作用,在治疗呼吸道病毒疾病方面具有独特的优势。本文综合目前天然药物防治呼吸道病毒的研究进展,以天然药物抗呼吸道病毒活性成分的作用机制进行分类,以期为未来的呼吸道疾病的临床治疗与药物发现提供参考依据。
Human viral respiratory disease is a kind of widely prevalent infectious disease.The incidence rate of respiratory virus infection occupies a major position in the overall structure of global incidence rate of residents,and is one of the main causes of acute and fatal human diseases.Natural products have diverse structures and novel mechanisms of action,which can regulate body immunity and resist respiratory viruses,and have unique advantages in the treatment of respiratory viral diseases.This article summarizes the current research progress of natural drugs in the prevention and treatment of respiratory viruses,classifies the action mechanism of the active components of natural drugs against respiratory viruses,to provide reference basis for clinical treatment and drug discovery of respiratory diseases in the future.
作者
王剑
张萍萍
于健
王京龙
崔清华
WANG Jian;ZHANG Ping-ping;YU Jian;WANG Jing-long;CUI Qing-hua(College of Food Science and Pharmaceutical Engineering,Zaozhuang University,Zaozhuang 277160,China;College of Pharmacy,Shandong University of Traditional Chinese Medicine,Jinan 250355,China)
出处
《药学学报》
CAS
CSCD
北大核心
2024年第4期853-865,共13页
Acta Pharmaceutica Sinica
基金
国家科技重大项目(2018ZX09101003)
山东省重点研发计划项目(2022TZXD0019)
枣庄学院博士科研启动基金项目(21/1020712).
作者简介
通讯作者:王剑,E-mail:hwangjian08@163.com;通讯作者:于健,E-mail:3179877749@qq.com。
