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首诊于精神科的脑淀粉样血管病1例

A case of cerebral amyloid angiopathy firstly visiting mental health department
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摘要 目的 探讨脑淀粉样血管病的临床症状及影像学表现。方法 回顾性分析1例首诊于精神科的脑淀粉样血管病的临床资料。结果 患者女性,56岁,临床主要表现为情感平淡、言语减少、记忆力减退。患者脑脊液蛋白0.51g/L,氯118.9mmol/L,潘氏试验弱阳性,脑电图α波不规则,慢波较多,磁敏感加权成像显示颅内弥漫性微出血,蒙特利尔认知评估11分,韦氏智力测试55分。给予甲强龙500 mg/d和罂粟碱90 mg/d治疗,出院2个月后复查,症状部分改善。结论 磁敏感加权成像对诊断脑淀粉样血管病具有较高的临床应用价值。 Objective To investigate the clinical symptoms and imaging manifestations of cerebral amyloid angiopathy(CAA).Methods The clinical data of a case who was first diagnosed with CAA in psychiatric department was retrospectively analyzed.Results The 58-year-old female patient had main clinical manifestations of plain emotion,reduced speech,and memory loss,with 0.51 g/L of cerebrospinal fluid protein,118.9 mmol/L of chlorine,weak positive in Pan's test,irregular electroencephalogram alpha wave,more slow wave,displaying diffuse intracranial microbleeding by susceptibility weighted imaging(SWI),11 points of Montreal cognitive assessment score(MCAS),55 points of Wechsler Intelligence Scale(WIS).The patient was managed by methylprednisolone(500 mg/d)and papaverine(90 mg/d),and the symptoms were partially improved after two months of discharge.Conclusion SWI has high clinical value in the diagnosis of CAA.
作者 马秀云 朱菊红 杨斌 Ma Xiuyun;Zhu Juhong;Yang Bin(Department of Mental Health,the Second Hospital of Lanzhou University,Lanzhou 730030,China)
出处 《临床荟萃》 CAS 2024年第1期61-64,共4页 Clinical Focus
关键词 脑淀粉样血管病 精神科 脑电描记术 脑脊液 磁敏感加权成像 cerebral amyloid angiopath psychiatry department electroencephalography cerebrospinal fluid susceptibility weighted imaging
作者简介 通信作者:杨斌,Email:156892477@qq.com。
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