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不同疗程高压氧治疗颅脑损伤患者的临床效果 被引量:2

Clinical effect of different courses of hyperbaric oxygen therapy on patients with craniocerebral injury
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摘要 目的观察不同疗程高压氧治疗对颅脑损伤患者的效果。方法选取山东第二医科大学附属益都中心医院2019年5月至2021年11月收治的80例颅脑损伤患者作为研究对象,按照随机数字表法分为试验组(40例)与对照组(40例)。在常规治疗的基础上,试验组加用高压氧治疗4疗程共60次,而对照组加用高压氧治疗2疗程共30次。经综合治疗80 d后,比较两组患者的临床总有效率、美国国立卫生研究院卒中量表评分(NIHSS)、日常生活活动能力量表评分(ADL)。结果试验组患者的临床治疗总有效率高于对照组,差异有统计学意义(P<0.01)。试验组患者治疗后的NIHSS评分低于对照组,ADL评分高于对照组,差异有统计学意义(P<0.05)。结论长疗程(>30次)高压氧治疗能更有效提高颅脑损伤患者神经功能、日常生活能力,值得临床推广。 Objective To observe the therapeutic effect of different courses of hyperbaric oxygen therapy on patients with craniocerebral injury.Methods A total of 80 patients with craniocerebral injury admitted to Yidu Central Hospital Affiliated to Shandong Second Medical University from May 2019 to November 2021 were selected as research objects,and they were divided into experimental group(40 cases)and control group(40 cases)according to random numbertable method.On the basis of conventional treatment,the experimental group was treated with hyperbaric oxygen for 60 times in 4 courses and the control group was treated with hyperbaric oxygen for 30 times in 2 courses.After 80 days of comprehensive treatment,the clinical total response rate,National Institutes of Health stroke scale score(NIHSS)and activity of daily living scale(ADL)score of the two groups were compared.Results The total effective rate of experimental group was higher than that of control group,the difference was statistically significant(P<0.01).The NIHSS score of the experimental group was lower than that of the control group after treatment,the difference was statistically significant(P<0.05),and the ADL score was higher than that of the control group,with statistical significance(P<0.01).Conclusion Long course(>30 times)of hyperbaric oxygen therapy can more effectively improve the neurological function and daily living ability of the patients with head injury,which is worthy of clinical promotion.
作者 张伟 赵振升 闵翠丽 国艳 刘海燕 常青 郭博升 ZHANG Wei;ZHAO Zhensheng;MIN Cuili;GUO Yan;LIU Haiyan;CHANG Qing;GUO Bosheng(Department of Neurosurgery,Yidu Central Hospital Affiliated to Shandong Second Medical University,Shandong Province,Weifang262500,China;Department of Hyperbaric Oxygen Therapy,Yidu Central Hospital Affiliated to Shandong Second Medical University,Shandong Province,Weifang262500,China;Department of Clinical Laboratory,Yidu Central Hospital Affiliated to Shandong Second Medical University,Shandong Province,Weifang262500,China;Department of Gastroenterology,Qingzhou People's Hospital,Shandong Province,Weifang262500,China;Library,Yidu Central Hospital Affiliated to Shandong Second Medical University,Shandong Province,Weifang262500,China)
出处 《中国当代医药》 CAS 2024年第4期62-66,共5页 China Modern Medicine
基金 山东省潍坊市卫健委科研项目(WFWSJK-2020-308)。
关键词 高压氧 颅脑损伤 不同疗程 美国国立卫生研究院卒中量表评分 日常生活活动能力量表评分 Hyperbaric oxygen Craniocerebral injury Different courses of treatment National Institutes of Health stroke scale score Activity of daily living scale score
作者简介 张伟(1982-),男,汉族,山东临朐人,博士,副主任医师,山东第二医科大学附属益都中心医院神经外科主任,研究方向:中枢神经系统肿瘤微创治疗。;通讯作者:赵振升(1978-),男,汉族,山东青州人,副主任医师,山东第二医科大学附属益都中心医院高压氧治疗科主任,研究方向:高压氧医学。
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