摘要
目的分析产后出血患者在接受卡前列素氨丁三醇注射液治疗时,联合应用子宫填塞球囊导管球囊压迫的止血效果,以及对凝血功能及不良反应的影响。方法选取福清市第二医院妇产科2019年1月—2023年1月收治的产后出血患者80例,随机分为对照组(n=40)与研究组(n=40)。对照组采用卡前列素氨丁三醇注射液联合创面缝合治疗,研究组采用卡前列素氨丁三醇注射液联合子宫填塞球囊导管球囊压迫治疗。比较2组的止血效果、凝血功能及不良反应情况。结果研究组的止血成功率(95.0%)显著高于对照组(77.5%)(P<0.05)。相比于对照组,研究组的手术操作时间及住院时间均更短(P<0.05),而输血量及24 h出血量则更少(P<0.05)。与对照组治疗后相比,研究组的纤维蛋白原(fibrinogen,FIB)水平更高(P<0.05),而凝血酶原时间(prothrombin time,PT)、活化部分凝血酶原时间(activated partial thromboplastin time,APTT)则更低(P<0.05)。研究组的术后感染、失血性休克、术后发热等不良反应发生率(10.0%)明显少于对照组(35.0%)(P<0.05)。结论在选择卡前列素氨丁三醇注射液治疗产后出血患者的前提下,联合应用子宫填塞球囊导管球囊压迫治疗操作简单方便,手术操作时间明显缩短,止血效果显著提升;而且能对患者凝血功能进行显著改善,不良反应少,具有较高的安全性。
Objective To analyze the hemostatic effect of combined use of uterine tamponade balloon catheter and balloon compression on postpartum hemorrhage patients receiving treatment with carboprost tromethamine injection,as well as its impact on coagulation function and adverse reactions.Methods A total of 80 postpartum hemorrhage patients admitted to department of gynecology,the Second Hospital of Fuqing City from January 2019 to January 2023 were randomly divided into a control group(n=40)and a study group(n=40).The control group was treated with carboprost tromethamine injection combined with wound suturing,while the study group was treated with carboprost tromethamine injection combined with uterine tamponade balloon catheter balloon compression.The hemostatic effects of the two groups were compared coagulation function and adverse reactions.Results The success rate of hemostasis in the study group(95.0%)was significantly higher than that in the control group(77.5%)(P<0.05).Compared to the control group,the study group had shorter surgical procedures and hospital stay(P<0.05),while the amount of blood transfusion and 24 h bleeding was lower(P<0.05).Compared with the control group after treatment,the study group had higher levels of fibrinogen(FIB)(P<0.05),while lower levels of prothrombin time(PT)and activated partial thromboplastin time(APTT)(P<0.05).The incidence of adverse reactions such as postoperative infection,hemorrhagic shock,and postoperative fever in the study group(10.0%)was significantly lower than that in the control group(35.0%)(P<0.05).Conclusion On the premise of choosing carboprost tromethamine injection to treat postpartum hemorrhage patients,the combined use of uterine tamponade balloon catheter and balloon compression therapy is simple and convenient,which can significantly shorten the surgical operation time and improve the hemostatic effect.Moreover,it can significantly improve the coagulation function of patients with minimal adverse reactions and high safety.
作者
徐晓街
陈建华
XU Xiaojie;CHEN Jianhua(Department of Gynaecology,the Second Hospital of Fuqing City,Fuqing Fujian 350300,China;Department of Nephrology,the Second Hospital of Fuqing City,Fuqing Fujian 350300,China)
出处
《中国卫生标准管理》
2024年第1期156-159,共4页
China Health Standard Management
关键词
产后出血
子宫球囊填塞
卡前列素氨丁三醇注射液
压迫治疗
止血效果
凝血功能
不良反应
postpartum hemorrhage
uterine balloon filling
carboprost tromethamine injection
compression therapy
hemostatic effect
coagulation function
adverse reactions
