摘要
目的分析孕产妇静脉血栓不良事件的临床特征、危险因素及评估方法。方法选取2021年1月-2022年6月在贵州省人民医院产科住院并发生静脉血栓不良事件的孕产妇43例作为病例组,以同期入院(±3天)约1∶3为匹配条件随机选取未发生静脉血栓不良事件者135例作为对照组。回顾性分析孕产妇静脉血栓不良事件的临床特征、危险因素、评估方法之间的差异。结果此研究中共43例孕产妇发生静脉血栓不良事件,其中发生在孕中期2例、孕晚期17例、产褥期24例,以产褥期为主。Spearman相关分析结果显示,年龄、ART/IVF、其他异常、多胎妊娠、子痫前期、高血压、分娩前D-二聚体与静脉血栓相关不良事件发生呈正相关(P<0.05)。Logistic回归分析显示,年龄、ART/IVF、高血压是静脉血栓相关不良事件发生的危险因素(P<0.05)。对Logistic回归模型进行模型拟合优度检验显示模型拟合度较好。结论孕产妇静脉血栓相关不良事件的早期预测及识别需针对危险因素进行个体化评估、动态评估、分层管理。
Objective To analyze the clinical features,risk factors and evaluation methods of adverse events of venous thrombosis adverse events in pregnant women.Methods A total of 43 pregnant women who were hospitalized in the obstetrics department of Guizhou Provincial People's Hospital from January 2021 to June 2022 with adverse events of venous thrombosis were selected as the case group,and 135 women who were hospitalized(±3 days)during the same period were randomly selected as the control group.The differences between clinical features,risk factors,assessment methods for adverse events of maternal venous thrombosis were retrospectively analyzed.Results In this study,there were 43 adverse events of venous thrombosis in pregnant women,including 2 in the second trimester,17 in the third trimester and 24 in the puerperal period,mainly in the puerperal period.Spearman correlation analysis showed that Age,ART/IVF,other abnormalities,multiple pregnancy,preeclampsia,hypertension,pre-delivery D-dimer were positively correlated with thrombose-related adverse events(P<0.05).Logistic regression analysis showed that age,ART/IVF and hypertension were risk factors for thrombose-related adverse events(P<0.05).The goodness of fit test of Logistic regression model shows that the model has a good fit.Conclusion Early prediction and identification of venous thrombosis-related adverse events in pregnant women need individualized assessment,dynamic assessment and hierarchical management for risk factors.
作者
赵舒
宋鸿碧
张佼
仲青
李晓庆
Zhao Shu;Song Hongbi;Zhang Jiao;Zhong Qing;Li Xiaoqing(Department of Obstetrics,Guizhou Provincial People's Hospital,Guiyang,Guizhou 550000,China)
出处
《首都食品与医药》
2023年第23期26-30,共5页
Capital Food Medicine
基金
贵州省卫生健康委2021年度科学技术基金项目(gzwkj2021-305)
贵州省科学技术厅2022年度科技厅临床专项(黔科合成果-LC[2022]003)。
关键词
静脉血栓栓塞
孕产妇
临床特征
危险因素
评估方法
Venous thromboembolism
Pregnant and parturient women
Clinical characteristics
Risk factors
Evaluation method
作者简介
通信作者:宋鸿碧,邮箱:610331504@qq.com。
