摘要
目的比较介入栓塞术和开颅夹闭术治疗颅内动脉瘤破裂的临床效果。方法选取2020年4月至2022年4月甘肃省人民医院收治的70例颅内动脉瘤破裂患者作为研究对象,按照手术方法不同分为研究组(35例)与对照组(35例),研究组采用介入栓塞术治疗,对照组采用开颅夹闭术治疗。比较两组的住院和手术相关指标(住院时间、住院费用、手术时间及术中出血量)、术后疼痛度、平均动脉压、预后及并发症。结果研究组手术时间、术中出血量及住院时间低于对照组,差异有统计学意义(P<0.05),研究组住院费用高于对照组,差异有统计学意义(P<0.05)。术后研究组患者疼痛程度低于对照组,差异有统计学意义(P<0.05)。术后研究组格拉斯哥预后量表评分高于对照组,改良Rankin量表评分及美国国立卫生院脑卒中量表评分均低于对照组,差异有统计学意义(P<0.05)。术后研究组平均动脉压降低效果优于对照组,差异有统计学意义(P<0.05)。术后研究组与对照组并发症率比较,差异无统计学意义(P>0.05)。结论对于颅内动脉瘤破裂患者,相较于传统开颅夹闭动脉瘤,介入栓塞术显示出了自身优势,可以缩短手术及住院时间,术后患者疼痛感知较弱,提升患者舒适度,改善预后。当然,介入栓塞术也应考虑患者家庭经济状况,在此之上,介入栓塞术更值得被考虑。
Objective To compare the clinical efficacy of interventional embolization and craniotomy in the treatment of ruptured intracranial aneurysm.Methods Seventy patients with ruptured intracranial aneurysms admitted to Gansu Provincial People's Hospital from April 2020 to April 2022 were selected as research objects.According to different surgical methods,they were divided into study group(35 cases)and control group(35 cases).The study group was treated with interventional embolization,while the control group was treated with craniotomy.Hospitalization and surgery-related indexes(length of stay,hospitalization cost,operation time and intraoperative blood loss),postoperative pain,blood pressure,prognosis and complications were compared between the two groups.Results The operation time,intraoperative blood loss and hospital stay of the study group were lower than those of the control group,the differences were statistically significant(P<0.05),the hospitalization cost of the study group was higher than that of the control group,the difference was statistically significant(P<0.05).Postoperative pain course of the study group was lower than that of the control group,and the difference was statistically significant(P<0.05).Glasgow outcome scale score of the study group was higher than that of the control group after surgery,modified Rankin scale score and National Institutes of Health stroke scale score were lower than that of the control group,the differences were statistically significant(P<0.05).The postoperative blood pressure reduction effect of the study group was better than that of the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the complication rate between the study group and the control group(P>0.05).Conclusion For patients with ruptured intracranial aneurysms,compared with traditional craniotomy clipped aneurysms,interventional embolization shows its own advantages,which can shorten the operation and hospital stay,reduce the postoperative pain perception of patients,improve the comfort level of patients and improve the prognosis.Of course,interventional embolization should also consider the financial status of the patient's family.On this basis,interventional embolization is more worthy of consideration.
作者
马勇
李红红
周宇
李斌
柴尔青
MA Yong;LI Honghong;ZHOU Yu;LI Bin;CHAI Erqing(School of Clinical Medicine,Ningxia Medical University,Ningxia Hui Autonomous Region,Yinchuan 750004,China;The Second Department of Respiratory,Gansu Provincial Maternity and Child-care Hospital,Gansu Province,Lanzhou 730000,China;Department of Cerebrovascular Diseases,Key Laboratory of Cerebrovascular Diseases of Gansu Province,Gansu Provincial Hospital,Gansu Province,Lanzhou 730000,China)
出处
《中国当代医药》
CAS
2023年第33期70-73,共4页
China Modern Medicine
基金
甘肃省卫生健康行业科研计划项目(GSWSQN2021-009)。
关键词
破裂颅内动脉瘤
介入栓塞术
开颅夹闭术
临床疗效
Ruptured intracranial aneurysm
Interventional embolization
Craniotomy clipping surgery
Clinical effect
作者简介
通讯作者:柴尔青。