摘要
目的 探讨2型糖尿病并发骨质疏松采用定量CT(quantitative computed tomography, QCT)及双能X线吸收仪(dual-energy X-ray absorptiometry, DXA)诊断的价值分析。方法 选取2021年1月-2023年1月珠海市人民医院收治的30例糖尿病患者(糖尿病组)和30例糖尿病并发骨质疏松患者(骨质疏松组)为研究对象,对比两组的血糖指标[空腹血糖(fasting plasma glucose, FPG)、餐后2 h血糖(2-hour postprandial blood glucose, 2 hPG)、糖化血红蛋白(glycated hemoglobin, HbA1c)]以及骨密度指标[腰椎L2、L3、L4的骨密度(bone mineral density, BMD)]。结果 两组FPG、2 hPG、空腹C肽(fasting C-peptide, FCP)、餐后2 h C肽(2 h C-peptide, 2 hCP)、HbA1c相比,差异有统计学意义(P<0.05)。两组的DXA和QCT的腰椎L2、L3、L4 BMD相比,差异有统计学意义(P<0.05)。结论 2型糖尿病并发骨质疏松采用QCT及BMD的应用价值较高,对于临床早期发现并治疗2型糖尿病患者合并骨质疏松具有重要临床意义。
Objective To evaluate the diagnostic value of quantitative computed tomography(QCT)and dual-energy X-ray absorptiometry(DXA)for type 2 diabetes mellitus complicated with osteoporosis.Methods Thirty patients with diabetes mellitus(diabetes group)and 30 patients with diabetes complicated with osteoporosis(osteoporosis group)ad-mitted to Zhuhai People's Hospital from January 2021 to January 2023 were selected as the study objects.glycemic in-dex[fasting plasma glucose(FPG),2-hour postprandial blood glucose(2 hPG)and glycated hemoglobin(HbA1c)],and bone mineral density[bone mineral density(BMD)of lumbar L2,L3,and L4]were compared between the two groups.Results There was statistically significant difference between the two groups in FPG,2 hPG,fasting C-peptide(FCP),2-hour C-peptide(2 hCP),and HbA1c(P<0.05).There was statistically significant difference in lumbar spine L2,L3,and L4 BMD between the two groups of DXA and QCT(P<0.05).Conclusion The application value of QCT and BMD for type 2 diabetes with osteoporosis is high,which has important clinical significance for early detection and treat-ment of type 2 diabetes patients with osteoporosis.
作者
黄樱
黄妙清
HUANG Ying;HUANG Miaoqing(Department of Endocrinology and Metabolism,Zhuhai People's Hospital(Zhuhai Hospital Affiliated to Jinan University School of Medicine),Zhuhai,Guangdong Province,519000 China)
出处
《糖尿病新世界》
2023年第17期31-33,38,共4页
Diabetes New World Magazine
基金
QCT和BMD在2型糖尿病合并骨质疏松作用和效能分析(2220009000151)。
关键词
2型糖尿病
骨质疏松
定量CT
骨密度
诊断价值
Type 2 diabetes mellitus
Osteoporosis
Quantitative CT
Bone mineral density
Diagnostic value
作者简介
黄樱(1980-),女,本科,副主任医师,研究方向为内分泌代谢(2型糖尿病、肥胖、骨质疏松)。
