摘要
类风湿关节炎(RA)不仅会严重损伤机体关节,还会累及关节外的脏器和组织,进而引发慢性肾脏病、肌少症、骨质疏松、冠心病、肺动脉高压等并发症。而这些并发症的发生可增加RA患者病情严重程度,影响疾病转归。25-羟维生素D[25(OH)D]在RA的发生发展中发挥重要作用,同时也与RA相关并发症的发生密切相关。因此,临床可通过检测25(OH)D水平早期预测RA患者相关并发症的发生风险,指导早期防治方案的制订,但关于25(OH)D水平在RA患者并发症发生风险方面的具体预测价值仍需未来进一步研究阐明。
Rheumatoid arthritis(RA)not only severely damages the body′s joints,but also affects extraarticular organs and tissues,leading to complications such as chronic kidney disease,sarcopenia,osteoporosis,coronary heart disease,and pulmonary hypertension.The occurrence of these complications can increase the severity of RA patients′condition and affect the prognosis of the disease.25-hydroxy vitamin D[25(OH)D]plays an important role in the occurrence and progression of RA,and is also closely related to the occurrence of RA related complications.Therefore,the risk of complications related to RA patients can be predicted early through testing 25(OH)D levels in clinical practice,guiding the development of early prevention and treatment plans.However,further research is needed to clarify the specific predictive value of 25(OH)D levels in the risk of complications in the RA patients.
作者
董文博
郭寰宇
于佳弘
DONG Wenbo;GUO Huanyu;YU Jiahong(Department of Clinical Laboratory,Lequn Branch,the First Hospital of Jilin University,Changchun 130031,China;Changchun University of Chinese Medicine,Changchun 130117,China)
出处
《医学综述》
CAS
2023年第17期3435-3439,共5页
Medical Recapitulate
作者简介
通信作者:郭寰宇,Email:ldew95211@163.com。
