中医辨证施治结合正念减压疗法对中晚期肝癌介入治疗患者生存率和生存质量的影响

Effect of TCM Treatment Based on Syndrome Differentiation Combined with Mindfulness-based Stress Reduction Therapy on Survival Rate and Quality of Life of Patients with Mid-to-advanced Liver Cancer Undergoing Interventional Therapy

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摘要目的:探究中医辨证施治结合正念减压疗法对中晚期肝癌介入治疗患者生存率及生存质量的影响。方法:选取南昌大学第一附属医院2021年1—7月收治的58例中晚期肝癌介入治疗患者作为研究对象,将其按随机数字表法分为两组,各29例。对照组患者接受常规治疗,研究组患者在对照组基础上接受中医辨证施治结合正念减压疗法。对比两组中医症候积分、心理韧性、癌因性疲乏、生存质量及治疗后3、6个月的生存率。结果:治疗前两组焦虑自评量表(SAS)、抑郁自评量表(SDS)及癌因性疲乏量表评分比较,差异均无统计学意义(P>0.05);治疗后,研究组以上各项指标评分相较于对照组均更低(P<0.05)。治疗后,研究组中医症候积分均较对照组更低,生存质量各项评分均高于对照组,差异均有统计学意义(P<0.05)。研究组治疗后3、6个月的生存率相较于对照组均更高,差异均有统计学意义(P<0.05)。结论:为中晚期肝癌介入治疗患者应用中医辨证施治结合正念减压疗法,能够缓解患者的不适症状,提高患者的心理韧性,改善生存质量,提高生存率。 Objective:To explore the effect of TCM treatment based on syndrome differentiation combined with mindfulness-based stress reduction therapy on survival rate and quality of life of patients with mid-toadvanced liver cancer undergoing interventional therapy.Method:A total of 58 patients with mid-to-advanced liver cancer underwent interventional therpy admitted to the First Affiliated Hospital of Nanchang University from January to July 2021 were selected as the study objects,and were divided into two groups according to random number table method,with 29 cases in each group.Patients in the control group received conventional treatment,and patients in the study group received TCM treatment based on syndrome differentiation combined with mindfulness-based stress reduction therapy on the basis of the control group.TCM syndromes score,mental toughness,cancer-related tiredness,quality of life and 3 and 6 months after treatment of survival rate were compared between the two groups.Result:There were no significant differences in self-rating anxiety scale(SAS),self-rating depression scale(SDS)and cancer-related tiredness scale scores between the two groups before treatment(P>0.05);after treatment,the scores of the above indexes in the study group were lower than those in the control group(P<0.05).After treatment,the scores of TCM symptoms in the study group were lower than those in the control group,and the scores of quality of life in the study group were higher than those in the control group,the differences were statistically significant(P<0.05).The survival rates of the study group at 3 and 6 months after treatment were higher than those of the control group,the differences were statistically significant(P<0.05).Conclusion:The application of TCM treatment based on syndrome differentiation combined with mindfulness-based stress reduction therapy in patients with mid-toadvanced liver cancer undergoing interventional therapy can alleviate the uncomfortable symptoms of patients,improve the mental toughness of patients,improve the quality of life and increase the survival rate.

作者夏青霜刘小红朱常好黄木华况圣佳曾小红罗荣光 XIA Qingshuang;LIU Xiaohong;ZHU Changhao;HUANG Muhua;KUANG Shengjia;ZENG Xiaohong;LUO Rongguang(The First Affiliated Hospital of Nanchang University,Nanchang 330006,China;不详)

机构地区南昌大学第一附属医院

出处《中国医学创新》 CAS 2023年第26期174-178,共5页 Medical Innovation of China

基金江西省中医药管理局科技计划项目(2022B773)。

关键词辨证施治正念减压疗法中晚期肝癌生存率生存质量 Treatment based on syndrome differentiation Mindfulness-based stress reduction therapy Mid-to-advanced liver cancer Survival rate Quality of life

分类号 R273 [医药卫生—中西医结合]

作者简介通信作者:夏青霜。