摘要
花青素是植物体内重要的次生代谢物,具有较强的药理活性,如抗氧化、抗癌等,广泛用于营养保健领域。自然条件下,植物体内的花青素以糖苷形式存在,带有各种糖基化修饰,而花青素糖基转移酶是专门负责催化这种糖基化反应的酶,能够把糖基供体转移到花青素不同的位点,形成了不同的花青素种类,从而改变这些分子的特性,影响生物活性和药用功能。本文重点综述了植物花青素糖基转移酶的分类和修饰反应特点,以及主要花青素资源植物中糖基转移酶的研究进展,有助于深入挖掘和鉴定植物中花青素相关糖基转移酶,解析其催化和调控机理,为花青素生物合成、富含花青素的植物资源研发提供新的思路。
Anthocyanins are important secondary metabolites in plants,with strong pharmacological activities such as antioxidation and anticancer,and are widely used in nutrition and health care fields.Under natural conditions,anthocy⁃anins in plants exist in the form of glucosides with various glycosylation modifications.Anthocyanin glycosyltransferases are enzymes specifically responsible for catalyzing this glycosylation reaction,which can transfer glycosyl donors to differ⁃ent sites of anthocyanins and form different types of anthocyanins,thus changing the properties of these molecules and af⁃fecting their biological activity and medicinal functions.The present study is performed to primarily review the classifica⁃tion and modification reaction characteristics of anthocyanin⁃related glycosyltransferases in plants,as well as the research progress of glycosyltransferases in major anthocyanin⁃rich plants.Findings in this study are expected to contribute to the comprehensive exploration and identification of anthocyanin⁃related glycosyltransferases in plants and analyze correspond⁃ing catalytic and regulatory mechanisms,so as to provide fresh ideas for anthocyanin biosynthesis,as well as research and development of anthocyanin⁃rich plant resources.
作者
顾佳珺
姚宇
落艳娇
王圆月
申国安
张丽娟
郭宝林
GU Jiajun;YAO Yu;LUO Yanjiao;WANG Yuanyue;SHEN Guoan;ZHANG Lijuan;GUO Baolin(School of Chinese Materia Medica,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicines,Ministry of Education,Institute of Medicinal Plant Development,Peking Union Medical College and Chinese Academy of Medical Sciences,Beijing 100193,China)
出处
《生物资源》
CAS
2023年第3期201-209,共9页
Biotic Resources
基金
国家自然科学基金项目(31570306)
中国医学科学院医学与健康科技创新工程项目(2021-I2M-1-031)
关键词
花青素
花青素资源植物
糖基转移酶
生物合成
基因工程
anthocyanin
anthocyanin resource plant
glycosyltransferase
biosynthesis
genetic engineering
作者简介
顾佳珺(1994-),女,研究生,主要从事植物次生代谢及调控研究。E-mail:junjunsayhello@126.com;通讯联系人:郭宝林(1966-),研究员,主要从事中药资源、鉴定、栽培研究。E-mail:guobaolin010@163.com。
