摘要
目的 探讨孕晚期B族链球菌(group B streptococcus, GBS)阴道直肠定植产妇分娩后新生儿早期干预效果分析。方法 随机选取2021年4月—2023年4月徐州仁慈医院妇产科孕龄>32周的100例GBS筛检阳性孕妇分娩后的新生儿,以随机数表法分为研究组与对照组,研究组新生儿娩出后立即予以阿莫西林颗粒口服,对照组未进行早期干预。比较两组血细胞数、CRP和PCT水平,以及新生儿GBS感染情况。结果 出生当日,两组PCT水平比较,差异有统计学意义(P<0.05);两组血细胞数、CRP水平比较,差异无统计学意义(P>0.05)。出生次日和第7日,研究组血细胞数、CRP和PCT水平低于对照组,差异有统计学意义(P<0.05)。共检出20例GBS感染,研究组早发性GBS疾病2例,无迟发性GBS疾病,对照组早发性GBS疾病11例,迟发性GBS疾病7例。研究组GBS感染发生率低于对照组,差异有统计学意义(P<0.05)。结论 适当的早期干预可显著降低新生儿GBS感染。
Objective To explore the effectiveness of early intervention for newborns after vaginal rectal colonization of group B streptococcus(GBS)in late pregnancy.Methods From April 2021 to April 2023,100 newborns of GBS screening positive pregnant women with gestational age>32 weeks in the obstetrics and gynecology department of Xuzhou Renci Hospital were randomly selected and divided into the study group and the control group by random number table.The study group newborns were given Amoxicillin granules orally immediately after delivery,while the control group did not receive early intervention.Compared the blood cell count,CRP and PCT levels,as well as the incidence of neonatal GBS infection between the two groups.Results On the day of birth,there was a statistically significant difference in PCT levels between the two groups(P<0.05);there was no statistically significant difference in blood cell count and CRP levels between the two groups(P>0.05).On the day after birth and the 7th day,the blood cell count,CRP,and PCT levels in the study group were lower than those in the control group,and the difference was statistically significant(P<0.05).A total of 20 cases of GBS infection were detected,with 2 cases of early onset GBS disease and no late onset GBS disease in the study group.There were 11 cases of early onset GBS disease and 7 cases of late onset GBS disease in the control group.The incidence of GBS infection in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Appropriate early intervention can significantly reduce GBS infection in newborns.
作者
李小艳
杨晓明
LI Xiaoyan;YANG Xiaoming(Department of Obstetrics,Xuzhou Renci Hospital,Xuzhou,Jiangsu Province,221000 China)
出处
《中外医疗》
2023年第19期37-40,共4页
China & Foreign Medical Treatment
基金
徐州仁慈医院集团科技创新课题非限制类技术(XZRCKY-KT-202204007)。
关键词
B族链球菌
感染
干预
效果分析
Group B streptococcus
Infection
Intervention
Effect analysis
作者简介
李小艳(1987-),女,本科,主治医师,主要从事产科临床研究工作;通信作者:杨晓明(1953-),女,本科,主任医师,主要从事产科临床研究工作,E-mail:83179687@qq.com。
