摘要
目的 探讨乙酰半胱氨酸溶液雾化吸入治疗脑梗死肺部感染的临床效果。方法 选择2021年1月—2023年1月赤峰市医院收治的60例脑梗死合并肺部感染患者为研究对象,以抽签法划分为对照组、研究组,各30例。对照组应用常规治疗+氨溴索静脉滴注,研究组应用乙酰半胱氨酸溶液雾化吸入治疗。比较两组治疗效果、肺部感染症状积分、临床指标、血气指标及安全性。结果 研究组总有效率为93.33%高于对照组的73.33%,差异有统计学意义(χ^(2)=4.320,P<0.05)。研究组治疗3、7、10 d时的肺部感染评分均低于对照组,差异有统计学意义(P<0.05)。研究组各项症状消失时间均短于对照组,差异有统计学意义(P<0.05)。治疗前,两组血气指标比较,差异无统计学意义(P>0.05)。治疗后,研究组各项血气指标均优于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论 雾化吸入乙酰半胱氨酸溶液治疗脑梗死患者肺部感染的效果显著,能够有效减轻感染症状、促进疾病转归,且有助于改善患者通气功能,疗效安全可靠。
Objective To investigate the clinical effect and application value of acetyl cysteine solution aerosol inhala‐tion in treating cerebral infarction and pulmonary infection.Methods From January 2021 to January 2023,60 patients with cerebral infarction complicated with pulmonary infection who were admitted to Chifeng Hospital were selected as the research objects.They were divided into the control group and the study group by drawing lots,with 30 cases in each group.The control group was treated with routine treatment+Ambroxol intravenous drip,and the study group was treated with acetylcysteine solution atomization inhalation.Compared the treatment efficacy,pulmonary infection symptom scores,clinical indicators,blood gas indicators,and safety between the two groups.Results The total effec‐tive rate of the study group was 93.33%,which was higher than 73.33%of the control group,the difference was statis‐tically significant(χ^(2)=4.320,P<0.05).The lung infection scores of the study group at 3 d,7 d,and 10 d of treatment were lower than those of the control group,the difference was statistically significant(P<0.05).The disappearance time of various symptoms in the study group was shorter than that in the control group,and the difference was statisti‐cally significant(P<0.05).There was no statistically significant difference in blood gas indicators between the two groups before treatment(P>0.05).After treatment,all blood gas indicators in the study group were better than those in the control group,the difference was statistically significant(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Atomized inhalation of acetylcyste‐ine solution has a significant effect on the treatment of pulmonary infection in patients with cerebral infarction,which can effectively reduce the symptoms of infection,promote the prognosis of disease,and help improve the ventilation function of patients.The efficacy is safe and reliable.
作者
荆瑞冬
张跃
计德丽
JING Ruidong;ZHANG Yue;JI Deli(Department of Neurology,Chifeng Hospital,Chifeng,Inner Mongolia Autonomous Region,024000 China)
出处
《系统医学》
2023年第9期98-102,共5页
Systems Medicine
关键词
雾化吸入治疗
乙酰半胱氨酸溶液
脑梗死
肺部感染
Atomizing inhalation therapy
Acetyl cysteine solution
Cerebral infarction
Pulmonary infection
作者简介
荆瑞冬(1988-),女,蒙古族,硕士,主治医师,研究方向为脑血管病;通信作者:计德丽(1986-),女,蒙古族,硕士,副主任医师,研究方向为眩晕、头痛,E-mail:15940126450@163.com。
