摘要
目的:探讨老年原发性高血压(essential hypertension,EH)患者三酰甘油葡萄糖(triglyceride-glucose,TyG)指数与高尿酸血症(hyperuricemia,HUA)的关系。方法:回顾性分析2021年3月—2022年8月江苏省人民医院溧阳分院收治的90例老年EH患者的临床资料。根据老年EH患者是否伴有HUA将其分为HUA组和非HUA组,收集所有患者的一般资料,并根据老年EH患者TyG指数的四分位数将其分为Q1~Q4组。分析HUA分组情况,比较HUA组和非HUA组一般资料,分析老年EH患者发生HUA的影响因素。比较Q1组、Q2组、Q3组、Q4组SUA水平及HUA发生率,分析老年EH患者中TyG指数与血尿酸(serum uric acid,SUA)水平的关系。结果:HUA组吸烟占比、三酰甘油(triglyceride,TG)、血肌酐(serum creatinine,Scr)、空腹血糖(fasting blood glucose,FBG)水平、TyG指数均高于非HUA组,差异有统计学意义(P<0.05)。吸烟、TG、Scr、FBG、TyG指数均为老年EH患者发生HUA的危险因素(P<0.05)。Q1~Q4组SUA水平和HUA发生率依次升高,差异有统计学意义(P<0.05)。Pearson分析结果显示,老年EH患者中TyG指数与SUA水平呈正相关(r=0.594,P<0.05)。结论:在老年EH患者中,TyG指数与SUA呈正相关,其为HUA的危险因素。
Objective:To investigate the relationship between triacylglycerol-glucose(TyG)index and hyperuricemia(HUA)in elderly patients with essential hypertension(EH).Method:Clinical data of 90 elderly EH patients admitted to Liyang Branch of Jiangsu Provincial People's Hospital from March 2021 to August 2022 were retrospectively analyzed.Elderly EH patients were divided into HUA group and non-HUA group according to whether they were accompanied by HUA.General data of all patients was collected,and elderly EH patients were divided into groups Q1 to Q4 according to the TyG index quartile.The situation of HUA grouping was analyzed,the general data of HUA group and non-HUA group were compared,and the influencing factors of HUA occurrence in elderly EH patients were analyzed.Serum uric acid(SUA)level and incidence of HUA in group Q1,group Q2,group Q3 and group Q4 were compared,and the relationship between TyG index and SUA level in elderly EH patients was analyzed.Result:The proportion of smoking,triglyceride(TG),serum creatinine(Scr),fasting blood glucose(FBG)levels and TyG index in HUA group were all higher than those in non-HUA group,the differences were statistically significant(P<0.05).Smoking,TG,Scr,FBG and TyG index were all risk factors for the occurence of HUA in elderly EH patients(P<0.05).SUA level and incidence of HUA in Q1 to Q4 groups were increased successively,the differences were statistically significant(P<0.05).Pearson analysis showed that TyG index was positively correlated with SUA level in elderly EH patients(r=0.594,P<0.05).Conclusion:In elderly EH patients,TyG index was positively correlated with SUA,which was also a risk factor for HUA.
作者
王丹
WANG Dan(Liyang Branch of Jiangsu Provincial People's Hospital,Liyang 213300,China)
出处
《中外医学研究》
2023年第17期147-150,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
