摘要
目的:探讨小剂量罗哌卡因联合舒芬太尼用于连续硬膜外麻醉在无痛分娩的可行性及安全性。方法:回顾我院2020年8月—2021年2月我院收治的102例拟行无痛分娩的孕妇作为研究对象,根据麻醉情况分成研究组和对照组,每组51例。对照组采用连续硬膜外罗哌卡因麻醉,研究组采用小剂量罗哌卡因联合舒芬太尼连续硬膜外麻醉。比较两组麻药起效时间、第一、第二、第三及总产程时间NRS评分、新生儿Apgar评分及并发症发生情况。结果:研究组麻醉麻药起效时间为(3.32±1.25)min,短于对照组的(6.89±1.93)min,差异有统计学意义(P<0.05);研究组第一产程、总产程短于对照组,差异有统计学意义(P<0.05),而两组第二、第三产程比较,差异无统计学意义(P>0.05);研究组镇痛后5、15、30、60 min及宫口开全时间点NRS评分低于对照组,差异有统计学意义(P<0.05);两组新生儿出生时、出生后1 min、5 min和10min时Apgar评分比较,差异无统计学意义(P>0.05);两组恶心、呕吐、头痛、尿潴留并发症发生率比较,差异无统计学意义(P>0.05)。结论:小剂量罗哌卡因联合舒芬太尼用于连续硬膜外麻醉在无痛分娩中的麻醉起效时间迅速,镇痛效果明显,且不增加不良反应发生风险。
Objective: To investigate the feasibility and safety of low-dose ropivacaine combined with sufentanil for continuous epidural anesthesia in painless delivery. Methods: From August 2020 to February 2021, 102 pregnant women who planned to undergo painless labor in our hospital were reviewed as the research objects. According to the anesthesia situation, they were divided into study group and control group, with 51 cases in each group. The control group was treated with continuous epidural ropivacaine anesthesia, and the study group was treated with low-dose ropivacaine combined with sufentanil continuous epidural anesthesia. The onset time of anesthetics, NRS scores of the first, second, third and total labor time, neonatal Apgar scores and complications were compared between the two groups. Results The onset time of anesthetic in the study group was(3.32±1.25) min, which was shorter than that in the control group(6.89±1.93) min,and the difference was statistically significant(P<0.05). The first and total stages of labor in the study group were shorter than those in the control group, and the difference was statistically significant(P<0.05), while the second and third stages of labor in the two groups were not statistically significant(P>0.05). The NRS score of the study group was lower than that of the control group at 5, 15, 30, 60 min after analgesia and the whole time point of uterine opening, and the difference was statistically significant(P<0.05). There was no significant difference in Apgar score between the two groups at birth, 1min,5min and 10min after birth(P>0.05). There were no significant differences in the incidence of complications of nausea,vomiting, headache and urinary retention between the two groups(P>0.05). Conclusion Low-dose ropivacaine combined with sufentanil in continuous epidural anesthesia in painless labor has rapid onset time, obvious analgesic effect, and does not increase the risk of adverse reactions..
作者
赵冬冬
于俊相
ZHAO Dongdong;Yu Junxiang(Department of Anesthesiology,Jinghai Hospital,Tianjin 301600,China)
出处
《中国药物滥用防治杂志》
CAS
2023年第1期49-52,共4页
Chinese Journal of Drug Abuse Prevention and Treatment
关键词
无痛分娩
罗哌卡因
硬膜外麻醉
镇痛效果
Painless delivery
Ropivacaine
Epidural anesthesia
Analgesic effect
作者简介
赵冬冬(1987.04-),男,汉族,安徽淮北人,本科,主治医师,主要研究方向:临床麻醉;通信作者:于俊相(1988.09-),男,汉族,天津人,本科,副主任医师,主要研究方向:临床麻醉。
