摘要
目的观察超脉冲二氧化碳点阵激光联合黄金微针射频治疗面部痤疮凹陷性瘢痕的疗效。方法选择2019年3月至2021年3月在河南大学第一附属医院皮肤科门诊按就诊顺序将符合诊断标准的面部痤疮凹陷性瘢痕病人70例,分为观察组和对照组,每组35例。观察组采用超脉冲二氧化碳点阵激光和黄金微针射频交替治疗,首次使用超脉冲二氧化碳点阵激光,间隔2周后用黄金微针射频。对照组采用黄金微针射频单独治疗,间隔4周。结果两组痤疮瘢痕临床评分量表(ECCA)权重评分治疗前观察组(52.29±20.48)分,对照组(51.43±26.58)分,组间比较,差异无统计学意义(Z=−0.49,P=0.623);治疗后观察组降至(23.29±15.43)分,治疗前后比较差异有统计学意义(Z=−4.73,P<0.001);对照组降至(37.14±19.03)分,治疗前后比较差异有统计学意义(Z=−3.48,P<0.001),治疗后两组比较,差异有统计学意义(Z=−3.16,P=0.002)。观察组治疗总有效率为91.43%,对照组为74.29%,组间比较,差异有统计学意义(χ^(2)=4.57,P=0.031)。观察组术后红肿持续、愈合及休工时间低于对照组,差异有统计学意义(P<0.001)。结论超脉冲二氧化碳点阵激光与黄金微针射频联合应用能够显著改善临床疗效,还可以减轻病人术后不良反应,两者联合应用,安全、有效,值得临床推广。
Objective To investigate the efficacy of an ultra-pulsed carbon dioxide fractional laser combined with gold microneedle radiofrequency in the treatment of facial acne depression scars.Methods A total of 70 patients with depressed facial acne scars who met the diagnostic criteria in the outpatient clinic of the Department of Dermatology of the First Affiliated Hospital of Henan University in the order of consultation from March 2019 to March 2021 were selected and divided into an observation group and a control group,with 35 patients in each group.The observation group was treated with alternating ultra-pulsed CO_(2) laser and gold microneedle radiofrequency,with the first use of ultra-pulsed CO_(2) fractional laser and 2-week interval followed by gold microneedle radiofrequency.The control group was treated with gold microneedle radiofrequency alone with an interval of 4 weeks.Results Before treatment,the weight scores of the acne scar clinical scale(ECCA)in the observation group(52.29±20.48)and the control group(51.43±26.58)were not statistically significant(Z=−0.49,P=0.623).After treatment,the observation group decreased to(23.29±15.43)points,and the difference was statistically significant when comparing before and after treatment(Z=−4.73,P<0.001).The control group decreased to(37.14±19.03)points,and the difference was statistically significant when comparing before and after treatment(Z=−3.48,P<0.001).The difference was statistically significant when comparing between the two groups after treatment(Z=−3.16,P=0.002).The overall effective rate was 91.43% in the observation group and 74.29% in the control group,with statistically significant differences between groups(χ^(2)=4.57,P=0.031).The duration of redness and swelling,healing and rest time after surgery were lower in the observation group than in the control group,and the difference was statistically significant(P<0.001).Conclusions The combination of an ultra-pulsed CO2 laser and gold microneedle radiofrequency can significantly improve the clinical efficacy and reduce the postoperative adverse reactions of patients.The combination of the two is safe,effective and worthy of clinical promotion.
作者
李小燕
聂磊
郭伟
程绍航
冯明智
LI Xiaoyan;NIE Lei;GUO Wei;CHENG Shaohang;FENG Mingzhi(Department of Dermatology,The First Affiliated Hospital of Henan University,Kaifeng,Henan 475001,China;Department of Dermatology,The People's Hospital of Longhua,Shenzhen,Guangdong 518000,China;Department of Dermatology,The Fifth People's Hospital of Suzhou,Suzhou,Jiangsu 215100,China)
出处
《安徽医药》
CAS
2023年第2期324-327,共4页
Anhui Medical and Pharmaceutical Journal
基金
开封市科技发展计划项目(1903103)。
关键词
寻常痤疮
瘢痕瘤性痤疮
脉冲射频术
二氧化碳点阵激光
黄金微针
痤疮瘢痕
Acne vulgaris
Acne keloid
Pulsed radiofrequency treatment
Ultra-pulse fractional CO_(2)fractional laser
Gold microneedle
Acne scar
作者简介
通信作者:聂磊,女,主任医师,研究方向为面部痤疮的综合治疗,Email:356838867@qq.com。
