摘要
目的分析南通市手足口病病原学监测结果,结合手足口病实际发病情况,探索病原学监测与其流行病学特点。方法按照监测方案的要求,对各区县上送的病例样品采用荧光定量聚合酶链式反应(PCR)方法进行手足口病病毒核酸检测,并通过中国疾病预防控制信息系统获取相关资料,利用SPSS等统计学工具分析相关数据特征。结果2018-2020年共采集手足口病监测样本1333份,平均检出率为66.24%,分型以Cox A6为主。2018和2019年两年每年各有两个高峰,4-8月为主高峰,8-11月为次高峰,2020年初受到新冠疫情影响,发病趋势不同于前两年。实际发病的三间分布与实验室监测结果基本一致。结论在实际发病数增加的情况下应相应增加监测病例的采样量并关注手足口病发病的区域分布变化,及时优化监测方案,使监测更加真实地反应手足口病的流行状况。
Objective The etiological surveillance result of hand-foot-mouth disease(HFMD)in Nantong were analyzed,and its epidemiological characteristics was explored in combination with the actual incidence of hand-foot-mouth disease.Methods According to the requirements of the surveillance program,the samples sent from each district and county were tested for HFMD virus nucleic acid by fluorescence quantitative PCR,and relevant data were obtained through the China Disease Control and Prevention Information System.Data was analyzed by SPSS and other statistical tools.Results A total of 1333 HFMD samples were collected from 2018 to 2020,with an average detection rate of 66.24%.Cox A6 was the dominant type.In 2018 and 2019,there were two peaks each year,with the main peak from April to August and the secondary peak from August to November.The incidence trend was different from that of the previous two years due to the impact of COVID-19 in early 2020.The distribution of the actual incidence was basically consistent with the laboratory monitoring result.Conclusions As the actual number of cases increases,the number of samples for monitoring should be increased accordingly,and the regional distribution of HFMD should be paid attention to,so as to optimize the monitoring scheme in time,so as to make the monitoring reflect the epidemic situation of HFMD more truly.
作者
苏婧
季霄雷
蔡秀丽
SU Jing;JI Xiao-lei;CAI Xiu-li(Nantong Center for Disease Control and Prevention,Jiangsu 226007,China)
出处
《首都公共卫生》
2022年第5期301-304,共4页
Capital Journal of Public Health
关键词
手足口病
流行病学
病原学
Cox
A6
Hand-foot-and-mouth disease
Epidemiology
Etiology
Cox A6
作者简介
通信作者:蔡秀丽,E-mail:624626497@qq.com。
